Qureshi Zaheer A, Shrestha Elina, Budhathoki Pravash, Ghazanfar Haider, Altaf Faryal, Dhallu Manjeet
Internal Medicine, Icahn School of Medicine at Mount Sinai, New York, USA.
Internal Medicine, BronxCare Health System, Bronx, USA.
Cureus. 2022 Jun 20;14(6):e26108. doi: 10.7759/cureus.26108. eCollection 2022 Jun.
Todd's paresis or phenomenon (TP) is a focal weakness in a part of the body after a seizure. Seizure is an abrupt change in behavior caused by the cerebral cortex's electrical hyper-synchronization of neuronal networks. After the seizure, there is usually a transition period from the ictal state to the pre-seizure baseline level of awareness and function, referred to as the postictal period. Postictal symptoms include many systems, including sensory, motor, and psychosis. This phenomenon is named after Robert Bentley Todd, who first described it. Todd's paresis can be confused with other conditions, most commonly a stroke. Postictal ocular manifestation may be accompanied by aphasia or hemiplegia, but isolated gaze palsy is rarely reported. We are reporting a rare and first known isolated ophthalmoparesis and ptosis as postictal findings with no structural abnormalities present in imaging studies and complete resolution over three weeks on its own as an atypical postictal phenomenon. Patients with an underlying structural abnormality of the brain are more susceptible to Todd's phenomenon. Unusual manifestations of Todd's phenomenon are rare but clinically relevant and are decisive in therapeutic decision-making. Our patient presents a rare manifestation of Todd's phenomenon as ptosis and ophthalmoparesis in an elderly male with no underlying structural brain abnormalities that resolved within three weeks. Further research into the causes is needed to distinguish it from a stroke.
托德麻痹或现象(TP)是癫痫发作后身体某部位的局灶性无力。癫痫发作是由神经元网络的大脑皮质电活动过度同步化引起的行为突然改变。癫痫发作后,通常有一个从发作状态到发作前意识和功能基线水平的过渡期,称为发作后期。发作后症状包括多个系统,包括感觉、运动和精神症状。这种现象以首次描述它的罗伯特·本特利·托德命名。托德麻痹可能与其他病症混淆,最常见的是中风。发作后眼部表现可能伴有失语或偏瘫,但孤立性凝视麻痹很少见报道。我们报告了一例罕见且首次发现的孤立性眼肌麻痹和上睑下垂作为发作后表现,影像学检查未发现结构异常,且在三周内自行完全缓解,这是一种非典型的发作后现象。有潜在脑结构异常的患者更容易出现托德现象。托德现象的不寻常表现很少见,但具有临床相关性,对治疗决策具有决定性意义。我们的患者表现出托德现象的罕见表现,即一名老年男性出现上睑下垂和眼肌麻痹,无潜在脑结构异常,且在三周内缓解。需要进一步研究其病因以将其与中风区分开来。