Great Lakes Institute for Environmental Research, University of Windsor , 401 Sunset Avenue, Windsor, Ontario Canada , N9B 3P4.
Environ Sci Technol. 2015 Jan 6;49(1):123-31. doi: 10.1021/es503427r. Epub 2014 Dec 9.
Polychlorinated biphenyls (PCBs) remain chemicals of concern more than three decades after the ban on their production. Technical mixture-based total PCB measurements are unreliable due to weathering and degradation, while detailed full congener specific measurements can be time-consuming and costly for large studies. Measurements using a subset of indicator PCBs (iPCBs) have been considered appropriate; however, inclusion of different PCB congeners in various iPCB schemes makes it challenging to readily compare data. Here, using an extensive data set, we examine the performance of existing iPCB3 (PCB 138, 153, and 180), iPCB6 (iPCB3 plus 28, 52, and 101) and iPCB7 (iPCB6 plus 118) schemes, and new iPCB schemes in estimating total of PCB congeners (∑PCB) and dioxin-like PCB toxic equivalent (dlPCB-TEQ) concentrations in sport fish fillets and the whole body of juvenile fish. The coefficients of determination (R(2)) for regressions conducted using logarithmically transformed data suggest that inclusion of an increased number of PCBs in an iPCB improves relationship with ∑PCB but not dlPCB-TEQs. Overall, novel iPCB3 (PCB 95, 118, and 153), iPCB4 (iPCB3 plus 138) and iPCB5 (iPCB4 plus 110) presented in this study and existing iPCB6 and iPCB7 are the most optimal indicators, while the current iPCB3 should be avoided. Measurement of ∑PCB based on a more detailed analysis (50+ congeners) is also overall a good approach for assessing PCB contamination and to track PCB origin in fish. Relationships among the existing and new iPCB schemes have been presented to facilitate their interconversion. The iPCB6 equiv levels for the 6.5 and 10 pg/g benchmarks of dlPCB-TEQ05 are about 50 and 120 ng/g ww, respectively, which are lower than the corresponding iPCB6 limits of 125 and 300 ng/g ww set by the European Union.
多氯联苯（PCBs）在禁止生产三十多年后仍然是人们关注的化学物质。由于风化和降解，基于技术混合物的总 PCB 测量是不可靠的，而对于大型研究，详细的全同物具体测量可能既耗时又昂贵。使用一组指标性 PCBs（iPCBs）进行测量已被认为是合适的；然而，不同 iPCB 方案中包含的不同 PCB 同系物使得难以轻易比较数据。在这里，我们使用广泛的数据组来检验现有的 iPCB3（PCB 138、153 和 180）、iPCB6（iPCB3 加上 28、52 和 101）和 iPCB7（iPCB6 加上 118）方案以及新的 iPCB 方案在估计鱼块和幼鱼全鱼体中总 PCB 同系物（∑PCB）和类二恶英 PCB 毒性等效物（dlPCB-TEQ）浓度方面的性能。使用对数变换数据进行回归分析的决定系数（R(2)）表明，在 iPCB 中增加 PCB 数量可以改善与∑PCB 的关系，但不能改善与 dlPCB-TEQ 的关系。总体而言，本研究提出的新型 iPCB3（PCB 95、118 和 153）、iPCB4（iPCB3 加上 138）和 iPCB5（iPCB4 加上 110）以及现有的 iPCB6 和 iPCB7 是最理想的指标，而目前的 iPCB3 则应避免使用。基于更详细分析（50 多种同系物）的∑PCB 测量也是评估 PCB 污染和跟踪鱼类中 PCB 来源的一种好方法。还提出了现有和新型 iPCB 方案之间的关系，以方便它们之间的相互转换。对于 dlPCB-TEQ05 的 6.5 和 10 pg/g 基准，iPCB6 equiv 水平分别约为 50 和 120 ng/gww，低于欧盟设定的 125 和 300 ng/gww 的相应 iPCB6 限值。
