Ahmadkhaniha Reza, Nodehi Ramin Nabizadeh, Rastkari Noushin, Aghamirloo Hassan Mohammadi
Department of Human Ecology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Environmental Health Department, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
J Environ Health Sci Eng. 2017 Jul 4;15:15. doi: 10.1186/s40201-017-0278-y. eCollection 2017.
To date, despite the facts that pasteurized milk is the most consumed dairy product in Iran and its consumption has increased almost two fold during the last 10 years, no data are available concerning the concentrations of polychlorinated biphenyls (PCBs) in commercial cow milk in Iran market.
This study designed to determine the levels of PCBs in these products and to assess population exposure to PCBs by estimating the daily intakes. Pasteurized cows' milk samples (10 brands) were collected from local markets at two different seasons and analyzed using sensitive and reliable methods.
Based on the results all the indicator PCBs were detected and quantified in all of the samples, the mean ± SD concentration for the sum of the six congeners was 18.92 ± 14.36 ng g fat. None of the samples surpassed the provisional value established by the EU of 40 ng g fat. The sum of dioxin-like congeners, expressed as WHO-TEQ was 0.492 pg/g of fat which was considerably lower than the defined limit 3 pg/g fat, set for cow's milk. Furthermore, a similar DL-PCBs profile as other studies was found for analyzed samples. The results indicated that concentrations of DL-PCBs were very low, and all of milk samples were compliant with EC legislation. In addition, seasonal variations were not observed for DL- and NDL-PCBs levels ( values >0.05).
The estimated dietary intake for target population was 0.06 pg TEQ/kg of body weight/day, much smaller than the amounts declared by the World Health Organization as tolerable daily intake.
迄今为止，尽管巴氏杀菌牛奶是伊朗消费最多的乳制品，且其消费量在过去10年中几乎增长了两倍，但尚无关于伊朗市场上商业牛奶中多氯联苯（PCBs）浓度的数据。
本研究旨在测定这些产品中多氯联苯的含量，并通过估计每日摄入量来评估人群对多氯联苯的暴露情况。在两个不同季节从当地市场采集巴氏杀菌牛奶样本（10个品牌），并使用灵敏可靠的方法进行分析。
根据结果，所有样本中均检测并定量了所有指示性多氯联苯，六种同系物总和的平均±标准差浓度为18.92±14.36 ng/g脂肪。没有一个样本超过欧盟规定的40 ng/g脂肪的临时值。以WHO-TEQ表示的二噁英类同系物总和为0.492 pg/g脂肪，远低于为牛奶设定的3 pg/g脂肪的规定限值。此外，分析样本的二噁英类多氯联苯谱与其他研究相似。结果表明，二噁英类多氯联苯的浓度非常低，所有牛奶样本均符合欧盟法规。此外，未观察到二噁英类和非二噁英类多氯联苯水平的季节性变化（P值>0.05）。
目标人群的估计膳食摄入量为0.06 pg TEQ/千克体重/天，远低于世界卫生组织宣布的可耐受每日摄入量。
