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Bacterial meningitis in the United States, 1998-2007.美国 1998-2007 年细菌性脑膜炎流行情况。
N Engl J Med. 2011 May 26;364(21):2016-25. doi: 10.1056/NEJMoa1005384.
3
Pneumococcal meningitis post-cochlear implantation: potential routes of infection and pathophysiology.人工耳蜗植入术后的肺炎球菌性脑膜炎:潜在感染途径和发病机制。
Otolaryngol Head Neck Surg. 2010 Nov;143(5 Suppl 3):S15-23. doi: 10.1016/j.otohns.2010.08.010.
4
Temporal analysis of the incidence of meningitis in the Tehran metropolitan area, 1999-2005.1999-2005 年德黑兰大都市区脑膜炎发病率的时间分析。
Popul Health Metr. 2009 Dec 23;7:19. doi: 10.1186/1478-7954-7-19.
5
Transmission of Streptococcus pneumoniae in an urban slum community.肺炎链球菌在城市贫民窟社区的传播
J Infect. 2008 Sep;57(3):204-13. doi: 10.1016/j.jinf.2008.06.017. Epub 2008 Jul 30.
6
Follow-up of cochlear implant use in patients who developed bacterial meningitis following cochlear implantation.人工耳蜗植入后发生细菌性脑膜炎患者的人工耳蜗使用随访。
Laryngoscope. 2008 Aug;118(8):1467-71. doi: 10.1097/MLG.0b013e3181758154.
7
Can we prevent cochlear implant recipients from developing pneumococcal meningitis?我们能否预防人工耳蜗植入受者发生肺炎球菌性脑膜炎?
Clin Infect Dis. 2008 Jan 1;46(1):e1-7. doi: 10.1086/524083.
8
Assessment of the protective effect of pneumococcal vaccination in preventing meningitis after cochlear implantation.评估肺炎球菌疫苗接种对预防人工耳蜗植入术后脑膜炎的保护作用。
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9
Invasive meningococcal disease in children in Jerusalem.耶路撒冷儿童侵袭性脑膜炎球菌病
Epidemiol Infect. 2008 Jun;136(6):782-9. doi: 10.1017/S0950268807009259. Epub 2007 Jul 30.
10
Bacterial meningitis among cochlear implant recipients--Canada, 2002.2002年加拿大人工耳蜗植入受者中的细菌性脑膜炎
MMWR Suppl. 2006 Apr 28;55(1):20-4.

未接种多价结合疫苗儿童人工耳蜗植入术后细菌性脑膜炎:伊朗一项371例病例队列研究的简要报告

Bacterial Meningitis after Cochlear Implantation among Children without Polyvalent Conjugate Vaccine: A Brief Report of an Iranian Cohort Study on 371 Cases.

作者信息

Afsharpaiman Shahla, Amirsalari Susan, Ajalloueyan Mohammad, Saburi Amin

机构信息

Health Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.

New Hearing Technologies Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.

出版信息

Int J Prev Med. 2014 Aug;5(8):1067-70.

PMID:25489459
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4258670/
Abstract

BACKGROUND

Regarding risk of bacterial meningitis (BM) after Cochlear implantation (CI), it was suggested to receive polyvalent conjugate vaccine. We aimed to estimate the prevalence of BM post CI in child recipients who do not receive polyvalent vaccine.

METHODS

We enrolled 371 children who had received cochlear implants from 2007 to 2010. None of them received pre or post implantation polyvalent conjugate vaccine for BM. We followed all of them for BM for 2 years after implantation.

RESULTS

We detected only one female case of BM (0.3% of patients) with the age of 24 months. The mean age of noninfected children was 36.7 ± 23.2 months. The education level of parents was "college level or higher" in less than half of them, and about 65% of patients were products of consanguineous marriage.

CONCLUSIONS

Our findings indicated that the incidence of BM was not higher in our cochlear implanted children who did not receive immunization than patients from countries in which routine vaccination is done. We suggest that although proper immunization is recommended before surgery, this procedure could be performed without vaccination, especially in developing countries that face financial problems for preparing vaccines.

摘要

背景

关于人工耳蜗植入(CI)后细菌性脑膜炎(BM)的风险,有人建议接种多价结合疫苗。我们旨在评估未接种多价疫苗的儿童人工耳蜗植入受者中BM的患病率。

方法

我们纳入了2007年至2010年期间接受人工耳蜗植入的371名儿童。他们中没有一人在植入前或植入后接种用于预防BM的多价结合疫苗。我们在植入后对他们所有人随访了2年以观察是否发生BM。

结果

我们仅检测到1例24个月大的BM女性病例(占患者的0.3%)。未感染儿童的平均年龄为36.7±23.2个月。不到一半患者的父母受教育程度为“大学及以上”,约65%的患者为近亲结婚的产物。

结论

我们的研究结果表明,在未接受免疫接种的人工耳蜗植入儿童中,BM的发生率并不高于进行常规疫苗接种国家的患者。我们建议,虽然术前建议进行适当的免疫接种,但即使不接种疫苗也可以进行该手术,尤其是在面临疫苗制备资金问题的发展中国家。