Alanazi Ghadah A, Alrashidi Aumniyat S, Alqarni Khalid S, Khozym Saeed A Al, Alenzi Saad
From the Faculty of Medicine(Alanazi, Alrashidi), Tabuk University; from the Department of Otolaryngology (Alqarni, khozym, Alenzi), King Fahad Specialist Hospital, Tabuk, Kingdom of Saudi Arabia.
Saudi Med J. 2022 Dec;43(12):1300-1308. doi: 10.15537/smj.2022.43.12.20220426.
To investigate the incidence, risk factors, and management of meningitis in cochlear implant (CI)users.
A systematic review was carried out using PubMed, Scopus, Web of Science, and Cochrane Central Register. Articles were considered relevant if reported any data on incidence, clinical presentations, the role of vaccination, management, and outcomes of meningitis after CI.
A total of 32 studies including 27358 patients were included, and meningitis was reported in only 202 cases. Meningitis occurred in the period ranging from 1 day to 72 months after CI. A total of 55 patients received the pneumococcal vaccine, while 20 patients received the type B vaccine. A large number of participants (n=47) had associated anatomical malformations, while 62 had otitis media before meningitis. A total of 24 cases required revision surgery along with medical treatment. Full recovery was the outcome reported by the included studies in 19 patients.
Cochlear implant users seem to be at possible risk of bacterial meningitis at any time after implantation, especially in the presence of risk factors, such as otitis media and anatomical malformations of the cochlea.
探讨人工耳蜗（CI）使用者脑膜炎的发病率、危险因素及管理。
使用PubMed、Scopus、Web of Science和Cochrane中央注册库进行系统评价。如果文章报告了有关人工耳蜗植入后脑膜炎的发病率、临床表现、疫苗接种的作用、管理和结果的任何数据，则认为这些文章相关。
共纳入32项研究，涉及27358例患者，仅202例报告发生脑膜炎。脑膜炎发生在人工耳蜗植入后1天至72个月期间。共有55例患者接种了肺炎球菌疫苗，20例患者接种了B型疫苗。大量参与者（n = 47）伴有解剖学畸形，62例在发生脑膜炎前患有中耳炎。共有24例患者在接受药物治疗的同时需要进行翻修手术。纳入研究报告19例患者完全康复。
人工耳蜗使用者在植入后的任何时间似乎都有患细菌性脑膜炎的潜在风险，尤其是在存在中耳炎和耳蜗解剖学畸形等危险因素的情况下。
