• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

The use of human keratinocytes and human skin models for predicting skin irritation.

作者信息

van de Sandt J, Roguet R, Cohen C, Esdaile D, Ponec M, Corsini E, Barker C, Fusenig N, Liebsch M, Benford D, de Fraissinette A de B, Fartasch M

机构信息

Toxicology Division, TNO Nutrition and Food Research Institute, Utrechtseweg 48, 3704 HE Zeist, The Netherlands.

Life Sciences Research, L'Oréal Advanced Research, Central Department of Products Safety, 1 Avenue Eugene Schueller, 93600 Aulnay-sous-Bois, France.

出版信息

Altern Lab Anim. 1999 Sep-Oct;27(5):723-43. doi: 10.1177/026119299902700504.

DOI:10.1177/026119299902700504
PMID:25490286
Abstract
摘要

相似文献

1
The use of human keratinocytes and human skin models for predicting skin irritation.使用人角质形成细胞和人皮肤模型预测皮肤刺激性。
Altern Lab Anim. 1999 Sep-Oct;27(5):723-43. doi: 10.1177/026119299902700504.
2
HSP27 as a biomarker for predicting skin irritation in human skin and reconstructed organotypic skin model.热休克蛋白 27 作为预测人体皮肤和重建器官型皮肤模型中皮肤刺激的生物标志物。
Toxicol Lett. 2014 Apr 21;226(2):124-31. doi: 10.1016/j.toxlet.2014.01.043. Epub 2014 Feb 3.
3
Assessment of dermal toxicity of nanosilica using cultured keratinocytes, a human skin equivalent model and an in vivo model.采用培养角质形成细胞、人体皮肤等效模型和体内模型评估纳米二氧化硅的皮肤毒性。
Toxicology. 2010 Jan 12;267(1-3):178-81. doi: 10.1016/j.tox.2009.10.011. Epub 2009 Oct 20.
4
Property characterization of reconstructed human epidermis equivalents, and performance as a skin irritation model.重建人体表皮等效物的特性表征,以及作为皮肤刺激模型的性能。
Toxicol In Vitro. 2018 Dec;53:45-56. doi: 10.1016/j.tiv.2018.07.005. Epub 2018 Jul 25.
5
Identification of potential biomarkers for predicting acute dermal irritation by proteomic analysis.采用蛋白质组学分析鉴定预测急性皮肤刺激的潜在生物标志物
J Appl Toxicol. 2011 Nov;31(8):762-72. doi: 10.1002/jat.1630. Epub 2011 Apr 6.
6
Establishment and evaluation of immortalized human epidermal keratinocytes for an alternative skin irritation test.用于替代皮肤刺激性试验的永生化人表皮角质形成细胞的建立与评价
J Pharmacol Toxicol Methods. 2017 Nov-Dec;88(Pt 2):130-139. doi: 10.1016/j.vascn.2017.08.005. Epub 2017 Aug 19.
7
Rat epidermal keratinocyte organotypic culture (ROC) as a model for chemically induced skin irritation testing.大鼠表皮角质形成细胞器官型培养(ROC)作为化学诱导皮肤刺激性测试的模型。
Toxicol Appl Pharmacol. 2005 Nov 1;208(3):233-41. doi: 10.1016/j.taap.2005.02.014.
8
Follow-up to the ECVAM prevalidation study on in vitro tests for acute skin irritation. The European Centre for the Validation of Alternative Methods Skin Irritation Task Force report 2.欧洲替代方法验证中心(ECVAM)关于急性皮肤刺激性体外试验预验证研究的后续报告。欧洲替代方法验证中心皮肤刺激特别工作组报告2。
Altern Lab Anim. 2002 Jan-Feb;30(1):109-29. doi: 10.1177/026119290203000110.
9
In vitro skin irritation: facts and future. State of the art review of mechanisms and models.体外皮肤刺激:事实与未来。机制与模型的最新综述
Toxicol In Vitro. 2004 Jun;18(3):231-43. doi: 10.1016/j.tiv.2003.09.009.
10
Constructing Human Skin Equivalents on Porcine Acellular Peritoneum Extracellular Matrix for In Vitro Irritation Testing.构建猪去细胞腹膜外基质上的人皮肤等效物用于体外刺激性测试。
Tissue Eng Part A. 2016 Jan;22(1-2):111-22. doi: 10.1089/ten.TEA.2015.0209. Epub 2015 Dec 17.

引用本文的文献

1
Soil and Freshwater Bioassays to Assess Ecotoxicological Impact on Soils Affected by Mining Activities in the Iberian Pyrite Belt.用于评估伊比利亚黄铁矿带采矿活动影响土壤的生态毒理学影响的土壤和淡水生物测定法。
Toxics. 2022 Jun 28;10(7):353. doi: 10.3390/toxics10070353.
2
Annatto Oil Loaded Nanostructured Lipid Carriers: A Potential New Treatment for Cutaneous Leishmaniasis.载有红木籽油的纳米结构脂质载体:皮肤利什曼病的一种潜在新疗法。
Pharmaceutics. 2021 Nov 11;13(11):1912. doi: 10.3390/pharmaceutics13111912.
3
Selected Biomarkers Revealed Potential Skin Toxicity Caused by Certain Copper Compounds.
某些铜化合物导致的潜在皮肤毒性可通过选择生物标志物揭示。
Sci Rep. 2016 Nov 28;6:37664. doi: 10.1038/srep37664.
4
Application of orange essential oil as an antistaphylococcal agent in a dressing model.橙皮精油在敷料模型中作为抗葡萄球菌剂的应用。
BMC Complement Altern Med. 2012 Aug 16;12:125. doi: 10.1186/1472-6882-12-125.
5
Evaluation of the in vitro skin permeation of antiviral drugs from penciclovir 1% cream and acyclovir 5% cream used to treat herpes simplex virus infection.对用于治疗单纯疱疹病毒感染的1%喷昔洛韦乳膏和5%阿昔洛韦乳膏中抗病毒药物的体外皮肤渗透情况进行评估。
BMC Dermatol. 2009 Apr 2;9:3. doi: 10.1186/1471-5945-9-3.
6
Assessment of the potential skin irritation of lysine-derivative anionic surfactants using mouse fibroblasts and human keratinocytes as an alternative to animal testing.使用小鼠成纤维细胞和人角质形成细胞评估赖氨酸衍生阴离子表面活性剂的潜在皮肤刺激性,以替代动物试验。
Pharm Res. 2004 Sep;21(9):1637-41. doi: 10.1023/b:pham.0000041459.63362.6f.