抑郁症患者中孤立性促甲状腺激素水平升高的意义：临床评论
The significance of an isolated elevated TSH level in a depressed patient: a clinical commentary.
作者信息
Joffe Russell T, Sullivan Timothy B
机构信息
Staten Island University Hospital, New York Hofstra LIJ North Shore School of Medicine, Hempstead, New York.
Staten Island University Hospital, New York New York Medical College, Valhalla.
出版信息
Int J Psychiatry Med. 2014;48(3):167-73. doi: 10.2190/PM.48.3.b.
OBJECTIVE
To discuss the approach to the isolated finding of an elevated thyrotropin (TSH) level on routine biochemical screening of a depressed patient.
METHOD
A focused literature review as well as discussion of published clinical guidelines and the formulation of a rational clinical approach.
RESULTS
Screening for thyroid dysfunction is part of the routine assessment of the depressed patient. It is not uncommon for such patients to have an isolated elevation of TSH levels with nor laboratory or clinical features of thyroid disease. There is often misunderstanding about how to deal with this isolated laboratory finding which can lead to unnecessary investigation and treatment.
CONCLUSIONS
A rational approach to evaluation and management of an isolated elevated TSH level is suggested.
目的
探讨在对抑郁症患者进行常规生化筛查时，发现促甲状腺激素（TSH）水平升高这一孤立结果的处理方法。
方法
进行重点文献综述，并讨论已发表的临床指南，制定合理的临床处理方法。
结果
甲状腺功能障碍筛查是抑郁症患者常规评估的一部分。此类患者出现TSH水平孤立性升高且无甲状腺疾病的实验室或临床特征的情况并不少见。对于如何处理这一孤立的实验室检查结果常常存在误解，这可能导致不必要的检查和治疗。
结论
提出了评估和处理TSH水平孤立性升高的合理方法。
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