Suppr超能文献

甲状腺功能减退症患者焦虑和抑郁症状的患病率。

Prevalence of anxiety and depressive symptoms among patients with hypothyroidism.

作者信息

Bathla Manish, Singh Manpreet, Relan Pankaj

机构信息

Department of Psychiatry, MM Institute of Medical Sciences and Research, Mullana, Jandheri, Haryana, India.

Department of Medicine, MM Institute of Medical Sciences and Research, Mullana, Jandheri, Haryana, India.

出版信息

Indian J Endocrinol Metab. 2016 Jul-Aug;20(4):468-74. doi: 10.4103/2230-8210.183476.

Abstract

CONTEXT

The association between depression and thyroid function is well known. Both conditions express many similar symptoms, thus making the diagnosis and treatment difficult.

AIMS

To find the prevalence of anxiety and depressive symptoms among patients with hypothyroid.

SETTINGS AND DESIGN

Cross-sectional study.

MATERIALS AND METHODOLOGY

A total of 100 patients diagnosed as hypothyroidism were evaluated using Hamilton depression rating scale (HDRS) and Hamilton scale for anxiety (HAM-A).

STATISTICAL ANALYSIS USED

The data were analyzed using the SPSS for Windows version 17.0 software. The quantitative data were expressed in number and percentage. The results obtained were compared using the Chi-square test.

RESULTS

Females constituted 70% of the sample. A total of 60% reported some degree of depression based on HDRS (males - 56.63% and females - 64.29%) whereas about 63% out of the total patients screened showed some degree of anxiety (males -56.66% and females - 65.72%) based on HAM-A. The most common depressive symptom among the males was depressed mood (73.33%) and among females was gastrointestinal somatic symptoms (68.54%). The most common anxiety symptom among the males was depressed mood (70.0%) and among females was anxious mood (92.85%).

CONCLUSIONS

Psychiatric symptoms/disorders are common in patients with thyroid dysfunction.

摘要

背景

抑郁症与甲状腺功能之间的关联众所周知。这两种病症都表现出许多相似的症状,因此诊断和治疗都很困难。

目的

确定甲状腺功能减退患者中焦虑和抑郁症状的患病率。

设置与设计

横断面研究。

材料与方法

使用汉密尔顿抑郁量表(HDRS)和汉密尔顿焦虑量表(HAM - A)对总共100名被诊断为甲状腺功能减退的患者进行评估。

所用统计分析方法

使用SPSS for Windows 17.0软件对数据进行分析。定量数据以数字和百分比表示。使用卡方检验对所得结果进行比较。

结果

女性占样本的70%。根据HDRS,共有60%的患者报告有一定程度的抑郁(男性 - 56.63%,女性 - 64.29%);而根据HAM - A,在所有接受筛查的患者中,约63%表现出一定程度的焦虑(男性 - 56.66%,女性 - 65.72%)。男性中最常见的抑郁症状是情绪低落(73.33%),女性中是胃肠道躯体症状(68.54%)。男性中最常见的焦虑症状是情绪低落(70.0%),女性中是焦虑情绪(92.85%)。

结论

精神症状/障碍在甲状腺功能障碍患者中很常见。

相似文献

1
Prevalence of anxiety and depressive symptoms among patients with hypothyroidism.
Indian J Endocrinol Metab. 2016 Jul-Aug;20(4):468-74. doi: 10.4103/2230-8210.183476.
2
Psychiatric symptoms and diagnoses in thyroid disorders: a cross-sectional study.
Int J Psychiatry Clin Pract. 2005;9(3):187-92. doi: 10.1080/13651500510029129.
3
Depression and anxiety in hypothyroidism.
West Indian Med J. 2003 Sep;52(3):223-7.
4
Is poststroke depression a major depression?
Cerebrovasc Dis. 2013;35(4):385-91. doi: 10.1159/000348852. Epub 2013 Apr 30.
5
Depressive symptoms in involuntary hospitalized patients in Cyprus: Socio-demographic and psychopathological characteristics.
Psychiatriki. 2021 Dec 20;32(4):300-310. doi: 10.22365/jpsych.2021.026. Epub 2021 Aug 5.
6
Prevalence of depression among hypothyroid patients attending the primary healthcare and endocrine clinics of King Fahad Hospital of the University (KFHU).
J Family Med Prim Care. 2019 Aug 28;8(8):2708-2713. doi: 10.4103/jfmpc.jfmpc_456_19. eCollection 2019 Aug.
7
A comparison of the dimensionality of the Hamilton Rating Scale for anxiety and the DSM-5 Anxious-Distress Specifier Interview.
Psychiatry Res. 2020 Feb;284:112788. doi: 10.1016/j.psychres.2020.112788. Epub 2020 Jan 13.

引用本文的文献

1
A Genetically-Engineered Thyroid Gland Built for Selective Triiodothyronine Secretion.
Int J Mol Sci. 2025 Jul 24;26(15):7166. doi: 10.3390/ijms26157166.
2
Correlation between depressive-like behavior and gut microbiota in mice with hypothyroidism.
World J Psychiatry. 2025 Jul 19;15(7):104921. doi: 10.5498/wjp.v15.i7.104921.
3
Hippocampal NLRP1 inflammasome mediates anxiety-like behavior in mice with hypothyroidism.
Sci Rep. 2025 May 9;15(1):16176. doi: 10.1038/s41598-025-00979-3.
5
Anxiety Symptoms in Hypothyroidism: A Case for Causation or Co-Occurrence?
Cureus. 2025 Jan 22;17(1):e77814. doi: 10.7759/cureus.77814. eCollection 2025 Jan.
7
Association between depression and anxiety disorders with euthyroid Hashimoto's thyroiditis: A systematic review and meta-analysis.
Compr Psychoneuroendocrinol. 2024 Dec 2;20:100279. doi: 10.1016/j.cpnec.2024.100279. eCollection 2024 Nov.
8
Depression in patients with chronic otolaryngology symptoms - A vicious cycle.
Head Face Med. 2024 Nov 15;20(1):68. doi: 10.1186/s13005-024-00464-8.
10
Frequency and Determinants of Depression in Hypothyroidism Patients at a Tertiary Care Hospital in the Western Region of Saudi Arabia.
Saudi J Med Med Sci. 2024 Jul-Sep;12(3):259-265. doi: 10.4103/sjmms.sjmms_261_23. Epub 2024 Jun 20.

本文引用的文献

1
Sexual function and depressive symptoms in young women with thyroid autoimmunity and subclinical hypothyroidism.
Clin Endocrinol (Oxf). 2016 Jun;84(6):925-31. doi: 10.1111/cen.12956. Epub 2015 Oct 19.
2
A biopsychosocial approach to primary hypothyroidism: treatment and harms data from a randomized controlled trial.
Chiropr Man Therap. 2015 Aug 20;23:24. doi: 10.1186/s12998-015-0068-5. eCollection 2015.
3
Subclinical Thyroid Dysfunction and Depressive Symptoms among the Elderly: A Prospective Cohort Study.
Neuroendocrinology. 2016;103(3-4):291-9. doi: 10.1159/000437387. Epub 2015 Jul 14.
4
The Relationship between Thyroid Function and Depressive Symptoms-the FIN-D2D Population-Based Study.
Clin Med Insights Endocrinol Diabetes. 2015 Apr 20;8:29-33. doi: 10.4137/CMED.S24111. eCollection 2015.
5
Diagnosed thyroid disorders are associated with depression and anxiety.
Soc Psychiatry Psychiatr Epidemiol. 2015 Sep;50(9):1417-25. doi: 10.1007/s00127-015-1043-0. Epub 2015 Mar 17.
7
Mood and anxiety disorders as early manifestations of medical illness: a systematic review.
Psychother Psychosom. 2015;84(1):22-9. doi: 10.1159/000367913. Epub 2014 Dec 24.
8
9
Is suppressed thyroid-stimulating hormone (TSH) associated with subclinical depression in the Danish General Suburban Population Study?
Nord J Psychiatry. 2015 May;69(4):282-6. doi: 10.3109/08039488.2014.972454. Epub 2014 Nov 7.
10
Increased psychiatric morbidity before and after the diagnosis of hypothyroidism: a nationwide register study.
Thyroid. 2014 May;24(5):802-8. doi: 10.1089/thy.2013.0555. Epub 2014 Jan 29.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验