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人类细小病毒(HPV/B19)感染伴紫癜

Human parvovirus (HPV/B19) infection with purpura.

作者信息

Shiraishi H, Umetsu K, Yamamoto H, Hatakeyama Y, Yaegashi N, Sugamura K

机构信息

Miyagi Prefectural Institute of Public Health.

出版信息

Microbiol Immunol. 1989;33(4):369-72. doi: 10.1111/j.1348-0421.1989.tb01984.x.

DOI:10.1111/j.1348-0421.1989.tb01984.x
PMID:2549345
Abstract

A 33-year-old man complained of purpura (petechial hemorrhage) in chelidons, poples, axillae, and bilateral chest in addition to other symptoms such as lumbago, arthralgia, muscular pain, and fever. On the next day of the onset, human parvovirus (HPV/B19) antigen and HPV/B19 DNA were detected in his serum, and twelve days later IgM antibody to HPV/B19 became detectable. This case supports the relationship between purpura and HPV/B19 infection.

摘要

一名33岁男性除了有腰痛、关节痛、肌肉疼痛和发热等症状外,还主诉在手掌、腘窝、腋窝及双侧胸部出现紫癜(瘀点出血)。发病次日,在其血清中检测到人类细小病毒(HPV/B19)抗原和HPV/B19 DNA,12天后检测到HPV/B19 IgM抗体。该病例支持紫癜与HPV/B19感染之间的关系。

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引用本文的文献

1
Human parvovirus B19.人细小病毒B19
Clin Microbiol Rev. 2002 Jul;15(3):485-505. doi: 10.1128/CMR.15.3.485-505.2002.
2
Pathogenesis of human parvovirus B19 in rheumatic disease.人类细小病毒B19在风湿性疾病中的发病机制。
Ann Rheum Dis. 2000 Sep;59(9):672-83. doi: 10.1136/ard.59.9.672.