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纳洛酮对急性乙醇中毒的影响。一项脑电图研究。

Effect of naloxone on acute ethylic intoxication. An EEG study.

作者信息

Dawid-Milner M S, Díaz-Calavia E J, Fernández del Moral R, Santidrián S, Jiménez-Vargas J

机构信息

Departamento de Fisiología, Facultad de Medicina, Universidad de Navarra, Pamplona, Spain.

出版信息

Rev Esp Fisiol. 1989 Jun;45(2):203-6.

PMID:2549591
Abstract

EEG recording has been used to evaluate in cats the effect of naloxone on acute ethylic intoxication (AEI). Naloxone was administered both before and during the course of AEI. Results of the experiment showed that administration of naloxone before the AEI potentiates the toxic effect of alcohol. However, the administration of naloxone in a continuous way along the course of AEI significantly diminished the toxic effect of alcohol.

摘要

脑电图记录已被用于评估猫体内纳洛酮对急性乙醇中毒(AEI)的影响。在急性乙醇中毒过程之前及期间均给予纳洛酮。实验结果表明,在急性乙醇中毒之前给予纳洛酮会增强酒精的毒性作用。然而,在急性乙醇中毒过程中持续给予纳洛酮可显著降低酒精的毒性作用。

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