Host-Microbiota Interactions Laboratory, Wellcome Trust Sanger Institute, Cambridge, UK.
Host-Microbiota Interactions Laboratory, Wellcome Trust Sanger Institute, Cambridge, UK.
Cell Host Microbe. 2014 Dec 10;16(6):703-5. doi: 10.1016/j.chom.2014.11.012.
Competition for nutrients is a key factor controlling pathogen colonization within the gastrointestinal tract. In this issue, Ferreyra et al. (2014) and Curtis et al. (2014) show that diverse enteric pathogens can exploit a metabolic byproduct from the commensal microbiota, succinate, to enhance their own virulence expression and proliferation.
营养竞争是控制胃肠道病原体定植的关键因素。在本期中，Ferreyra 等人（2014 年）和 Curtis 等人（2014 年）表明，不同的肠道病原体可以利用共生微生物群落的代谢副产物琥珀酸来增强自身的毒力表达和增殖。
