Polnisch E, Hofmann K
Sektion Biologie, Ernst-Moritz-Arndt-Universität Greifswald, German Democratic Republic.
Arch Microbiol. 1989;152(3):269-72. doi: 10.1007/BF00409662.
The inactivation of fructose-1,6-bisphosphatase, isocitrate lyase and cytoplasmic malate dehydrogenase in Candida maltosa was found to occur after the addition of glucose to starved cells. The concentration of cyclic AMP and fructose-2,6-bisphosphate increased drastically within 30 s when glucose was added to the intact cells of this yeast. From these results it was concluded that catabolite inactivation, with participation of cyclic AMP and fructose-2,6-bisphosphate, is an important control mechanism of the gluconeogenetic sequence in the n-alkane-assimilating yeast Candida maltosa, as described for Saccharomyces cerevisiae.
在麦芽糖假丝酵母中，发现向饥饿细胞添加葡萄糖后，果糖-1,6-二磷酸酶、异柠檬酸裂解酶和细胞质苹果酸脱氢酶会失活。当向这种酵母的完整细胞添加葡萄糖时，环磷酸腺苷（cAMP）和果糖-2,6-二磷酸的浓度在30秒内急剧增加。从这些结果可以得出结论，如酿酒酵母所述，在环磷酸腺苷和果糖-2,6-二磷酸参与下的分解代谢物失活是同化正构烷烃的酵母麦芽糖假丝酵母中糖异生序列的重要控制机制。
