Zhang Zhaoyan, Chhetri Dinesh K, Bergeron Jennifer L
Department of Head and Neck Surgery, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California.
Department of Head and Neck Surgery, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California.
J Voice. 2015 Mar;29(2):230-5. doi: 10.1016/j.jvoice.2014.07.003. Epub 2014 Dec 9.
Medialization laryngoplasty is commonly used to treat glottic insufficiency. In this study, we investigated the effects of implant stiffness (Young modulus), medialization depth, and implant medial surface shape on acoustic outcomes.
Basic science study using ex vivo laryngeal phonation model.
In an ex vivo human larynx phonation model, bilateral medialization laryngoplasties were performed with implants of varying stiffness, medial surface shape (rectangular, divergent, and convergent), and varying depths of medialization. The subglottal pressure, the flow rate, and the outside sound were measured as the implant parameters were varied.
Medialization through the use of implants generally improved the harmonic-to-noise ratio (HNR) and the number of harmonics excited in the outside sound spectra. The degree of acoustic improvement depended on the implant insertion depth, stiffness, and to a lesser degree implant shape. Varying implant insertion depth led to large variations in phonation for stiff implants, but had much smaller effects for soft implants.
Implants with stiffness comparable to vocal folds provided more consistent improvement in acoustic outcomes across different implant conditions. Further investigations are required to better understand the underlying mechanisms.
喉内移成形术常用于治疗声门闭合不全。在本研究中,我们调查了植入物硬度(杨氏模量)、内移深度和植入物内侧表面形状对声学结果的影响。
使用离体喉发声模型的基础科学研究。
在离体人喉发声模型中,使用不同硬度、内侧表面形状(矩形、发散形和收敛形)以及不同内移深度的植入物进行双侧喉内移成形术。在改变植入物参数时,测量声门下压力、流速和外部声音。
通过使用植入物进行内移通常可提高谐波与噪声比(HNR)以及外部声音频谱中激发的谐波数量。声学改善程度取决于植入物插入深度、硬度,在较小程度上还取决于植入物形状。改变植入物插入深度会导致硬植入物发声有很大变化,但对软植入物的影响要小得多。
硬度与声带相当的植入物在不同植入条件下能更一致地改善声学结果。需要进一步研究以更好地理解其潜在机制。