Lundy Donna S, Casiano Roy R, McClinton Mark E, Xue Jun W
University of Miami School of Medicine, The Department of Otolaryngology, Miami, Florida 33101, USA.
J Voice. 2003 Dec;17(4):589-95. doi: 10.1067/s0892-1997(03)00081-x.
Medialization thyroplasty (type I) has become the gold standard to improve glottic closure due to unilateral vocal fold paralysis. A newer injection method utilizing homologous collagen from cadaveric human tissue has been described as an attractive alternative as no donor site is required, there is a very low risk of hypersensitivity, and the intact, acellular collagen fibers may suffer a reduced long-term reabsorption rate. Preliminary results on eight patients comparing presurgical and postsurgical parameters (perceptual, stroboscopic, acoustic, and aerodynamic) revealed comparable results when compared with a control group of individuals, age- and sex-matched, that had undergone standard medialization thyroplasty (type I). Further study is needed to assess the long-term results with this minimally invasive method of vocal fold medialization.
Ⅰ型甲状软骨内移成形术已成为改善单侧声带麻痹所致声门闭合的金标准。一种利用来自尸体人体组织的同源胶原蛋白的新型注射方法被描述为一种有吸引力的替代方法，因为无需供区，过敏风险极低，完整的无细胞胶原纤维可能具有较低的长期再吸收率。对8例患者术前和术后参数（感知、频闪喉镜、声学和空气动力学）进行比较的初步结果显示，与年龄和性别匹配、接受标准Ⅰ型甲状软骨内移成形术的对照组相比，结果相当。需要进一步研究以评估这种声带内移微创方法的长期效果。
