肺炎克雷伯菌K12荚膜多糖中5,6-O-(1-羧基亚乙基)-D-呋喃半乳糖单元存在的证据。
Proof of the occurrence of 5,6-O-(1-carboxyethylidene)-D-galactofuranose units in the capsular polysaccharide of Klebsiella K12.
作者信息
Beurret M, Joseleau J P, Vignon M, Dutton G G, Savage A V
机构信息
Centre de Recherches sur les Macromolécules Végétales, C.N.R.S., associé à l'Université Scientifique et Médicale de Grenoble, Saint-Martin d'Hères, France.
出版信息
Carbohydr Res. 1989 Jun 15;189:247-60. doi: 10.1016/0008-6215(89)84101-1.
The 13C-n.m.r. spectra of the capsular polysaccharide of Klebsiella K41 and phage-derived oligosaccharides K41-P1 and K41-P2 were compared with spectra from the structurally similar polysaccharide of Klebsiella K12 and oligosaccharides K12-P1 and K12-P2. This led to the conclusion that K41 and K12 contain one and two galactofuranose residues per repeating unit, respectively, and that the terminal, lateral residue in K12 has the 5,6-O-(1-carboxyethylidene)-D-galactofuranose structure rather than that of a 4,6-acetal of D-galactopyranose as originally stated. This is the first reported occurrence in Nature of such a structural unit.
将肺炎克雷伯菌K41的荚膜多糖以及噬菌体衍生的低聚糖K41 - P1和K41 - P2的13C - 核磁共振谱，与结构相似的肺炎克雷伯菌K12的多糖以及低聚糖K12 - P1和K12 - P2的谱图进行了比较。由此得出结论，K41和K12每个重复单元分别含有一个和两个呋喃半乳糖残基，并且K12中的末端横向残基具有5,6 - O -（1 - 羧基亚乙基）- D - 呋喃半乳糖结构，而非最初所述的D - 吡喃半乳糖的4,6 - 缩醛结构。这是首次报道在自然界中出现这种结构单元。
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