Lin Zheng-Yu, Song Qian-Qian, Chen Jin, Wan Ren-Jun, Zheng Hui, Chen Zhong-Wu, Chen Yi-Ping, Hua Wang-Chun
The Department of Intervention, First Affiliated Hospital of Fujian Medical University, 20 Chazhong Road, Fuzhou, 350005, China,
Tumour Biol. 2015 Mar;36(3):2105-10. doi: 10.1007/s13277-014-2819-7. Epub 2014 Dec 14.
Radiofrequency ablation (RFA) is one of the treatment modes for liver cancer. The trauma caused by RFA is small, and its local curative effect is reliable. Computed tomography (CT) can only be used for axial scans, and parts of the lesion are unclear on plain scans. The aim of this study is to compare the local curative effect of RFA percutaneously guided by MRI and ultrasound for small hepatocellular carcinoma (HCC). This study is a retrospective study. In this study, we examined 60 cases of 88 liver lesions and 50 cases of 52 lesions, in which RFA was guided by MRI and ultrasound, respectively. All cases were clinically diagnosed. The therapeutic effect of ablation lesions was examined by postoperative imaging follow-up. The results indicated that there were 5 (5/88) recurrences of liver lesions with MRI-guided RFA and 14 (14/52) recurrences of liver lesions with ultrasound-guided RFA. The median time to recurrence in the case of recurrent lesions was 7 months. Postoperative ablation lesions showed a low-intensity signal surrounded by a thin high-intensity signal ring on T2WI images. On T1WI images, the ablation lesion showed a concentric pattern and the central area of the original lesion continued to show a low-intensity signal with a clear ring of high-intensity signal that had a clear boundary. In conclusion, the local curative effect of MRI-guided RFA for small HCC is superior to that of ultrasound-guided RFA.
射频消融术（RFA）是肝癌的治疗方式之一。RFA造成的创伤较小，其局部治疗效果可靠。计算机断层扫描（CT）仅能用于轴向扫描，平扫时部分病灶显示不清。本研究的目的是比较磁共振成像（MRI）和超声引导下经皮射频消融术治疗小肝细胞癌（HCC）的局部疗效。本研究为回顾性研究。在本研究中，我们分别检查了88个肝脏病灶中的60例和52个病灶中的50例，其中RFA分别由MRI和超声引导。所有病例均经临床诊断。通过术后影像学随访检查消融病灶的治疗效果。结果显示，MRI引导下RFA治疗的肝脏病灶有5例（5/88）复发，超声引导下RFA治疗的肝脏病灶有14例（14/52）复发。复发病灶的中位复发时间为7个月。术后消融病灶在T2加权成像（T2WI）图像上表现为低强度信号被薄的高强度信号环包围。在T1加权成像（T1WI）图像上，消融病灶呈同心圆模式，原病灶的中心区域继续表现为低强度信号，有清晰的高强度信号环，边界清晰。总之，MRI引导下RFA治疗小肝癌的局部疗效优于超声引导下RFA。
