Clustal欧米伽

Clustal omega.

作者信息

Sievers Fabian, Higgins Desmond G

机构信息

School of Medicine and Medical Science, Conway Institute, University College Dublin, Ireland.

出版信息

Curr Protoc Bioinformatics. 2014 Dec 12;48:3.13.1-3.13.16. doi: 10.1002/0471250953.bi0313s48.

DOI:10.1002/0471250953.bi0313s48

PMID:25501942

Abstract

Clustal Omega is a package for making multiple sequence alignments of amino acid or nucleotide sequences, quickly and accurately. It is a complete upgrade and rewrite of earlier Clustal programs. This unit describes how to run Clustal Omega interactively from a command line, although it can also be run online from several sites. The unit describes a basic protocol for taking a set of unaligned sequences and producing a full alignment. There are also protocols for using an external HMM or iteration to help improve an alignment.

摘要

Clustal Omega是一个用于快速、准确地进行氨基酸或核苷酸序列多序列比对的软件包。它是早期Clustal程序的全面升级和重写版本。本单元描述了如何从命令行交互式运行Clustal Omega，不过它也可以在多个网站上在线运行。本单元描述了一个用于获取一组未比对序列并生成完整比对的基本协议。还有使用外部隐马尔可夫模型（HMM）或迭代来帮助改进比对的协议。