Li Yali, Wan Zhe, Liu Wei, Li Ruoyu
Department of Dermatology and Venereology, Peking University First Hospital, Research Center for Medical Mycology, Peking University, and Beijing Key Laboratory of Molecular Diagnosis of Dermatoses, Beijing, People's Republic of China.
Department of Dermatology and Venereology, Peking University First Hospital, Research Center for Medical Mycology, Peking University, and Beijing Key Laboratory of Molecular Diagnosis of Dermatoses, Beijing, People's Republic of China
J Clin Microbiol. 2015 Feb;53(2):702-5. doi: 10.1128/JCM.03233-14. Epub 2014 Dec 10.
Molecular identification and in vitro antifungal susceptibility tests of 43 Aspergillus section Nigri isolates from China were performed. Aspergillus niger and Aspergillus tubingensis were present in almost equal numbers. All of the isolates had low MIC/MECs (minimum effective concentrations) for the 7 common antifungals, and a paradoxical effect was observed for the first time in response to caspofungin and micafungin.
对来自中国的43株黑曲霉属分离株进行了分子鉴定和体外抗真菌药敏试验。黑曲霉和土曲霉的数量几乎相等。所有分离株对7种常见抗真菌药物的最低抑菌浓度/最低有效浓度(MIC/MEC)都很低,并且首次观察到对卡泊芬净和米卡芬净有矛盾效应。