通过胸壁切除与重建完成对巨大磷尿性间叶肿瘤的切除。

Complete resection of a large phosphaturic mesenchymal tumour by chest wall resection and reconstruction.

作者信息

Okiror Lawrence, Khalil Haitham, Vaiyapuri Sumathi, Kalkat Maninder

机构信息

Department of Thoracic Surgery, 1st Floor Stratford House, Birmingham Heartlands Hospital, Bordesley Green, Birmingham, B9 5SS, UK.

Department of Oncoplastic and Reconstructive Surgery, Solihull Hospital, Birmingham, UK.

出版信息

Gen Thorac Cardiovasc Surg. 2016 Jun;64(6):355-8. doi: 10.1007/s11748-014-0505-8. Epub 2014 Dec 13.

DOI:10.1007/s11748-014-0505-8

PMID:25503563

Abstract

Phosphaturic mesenchymal tumour is an extremely rare mesenchymal neoplasm of bone or soft tissue. It is associated with paraneoplastic oncogenic osteomalacia through secretion of fibroblast growth factor-23 (FGF-23) which inhibits renal proximal tubule phosphate re-uptake. We report a case of a 36-year-old woman with a large chest wall tumour completely excised by extensive chest wall resection and reconstruction with polypropylene mesh-methylmethacrylate composite and pedicled muscle flaps.

摘要

磷尿性间叶肿瘤是一种极其罕见的骨或软组织间叶肿瘤。它通过分泌成纤维细胞生长因子-23（FGF-23）导致副肿瘤性致癌性骨软化，该因子会抑制肾近端小管对磷酸盐的重吸收。我们报告了一例36岁女性患者，其胸壁有一个大肿瘤，通过广泛的胸壁切除并用聚丙烯网-甲基丙烯酸甲酯复合材料和带蒂肌皮瓣进行重建，肿瘤被完全切除。