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[婴儿获得性巨细胞病毒感染相关的脑血管出血]

[Cerebrovascular hemorrhage associated with acquired cytomegalovirus infection in an infant].

作者信息

Muñoz Nelson, Pinzón Hernando, Vizcaíno Hugo, Moneriz Carlos

机构信息

Hospital Infantil Napoleón Franco Pareja, Cartagena, Colombia.

Departamento de Pediatría, Facultad de Medicina, Universidad de Cartagena.

出版信息

Biomedica. 2014 Oct-Dec;34(4):521-7. doi: 10.1590/S0120-41572014000400004.

DOI:10.1590/S0120-41572014000400004
PMID:25504240
Abstract

Cytomegalovirus is the most frequent causative agent of perinatal infection and a major cause of acquired viral infections. This case report aims to show the broad clinical spectrum of the presentation of cytomegalovirus infection. The correct classification of congenital or acquired infection and its prompt treatment can prevent complications and sequelae in severe cases. We report the case of an infant with acquired cytomegalovirus infection, which presented an unusual feature of cerebral hemorrhage. The patient was treated with ganciclovir, with a favorable evolution of the clinical symptoms. Cytomegalovirus infection is common in children, both in its congenital and acquired forms. Acquired infection, as portrayed in this case, is mainly characterized by hematological compromise given by the marked thrombocytopenia, which may rarely result in cases of bleeding in the central nervous system. In this patient, no important clinical implications occurred. In addition, most of the acquired infections are self-limited and require no treatment.

摘要

巨细胞病毒是围产期感染最常见的病原体,也是获得性病毒感染的主要原因。本病例报告旨在展示巨细胞病毒感染临床表现的广泛范围。正确区分先天性或获得性感染并及时治疗可预防严重病例的并发症和后遗症。我们报告了一例获得性巨细胞病毒感染的婴儿病例,该病例呈现出脑出血这一不寻常特征。患者接受了更昔洛韦治疗,临床症状有良好改善。巨细胞病毒感染在儿童中很常见,包括先天性和获得性感染形式。如本病例所示,获得性感染主要特征是明显血小板减少导致血液系统受损,这可能很少导致中枢神经系统出血病例。在该患者中,未出现重要临床影响。此外,大多数获得性感染是自限性的,无需治疗。

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[Cerebrovascular hemorrhage associated with acquired cytomegalovirus infection in an infant].[婴儿获得性巨细胞病毒感染相关的脑血管出血]
Biomedica. 2014 Oct-Dec;34(4):521-7. doi: 10.1590/S0120-41572014000400004.
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[Acquired cytomegalovirus infection in infants. A case successfully treated with ganciclovir].[婴儿获得性巨细胞病毒感染。1例用更昔洛韦成功治疗的病例]
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