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婴儿腹绞痛、反流和便秘:儿童功能性胃肠疾病发展过程中的早期创伤性损伤?

Infantile colic, regurgitation, and constipation: an early traumatic insult in the development of functional gastrointestinal disorders in children?

作者信息

Indrio Flavia, Di Mauro Antonio, Riezzo Giuseppe, Cavallo Luciano, Francavilla Ruggiero

机构信息

Pediatric Unit, Department of Biomedical Science and Human Oncology, University of Bari "Aldo Moro", Giovanni XXIII Hospital Via Amendola 270, 70126, Bari, Italy,

出版信息

Eur J Pediatr. 2015 Jun;174(6):841-2. doi: 10.1007/s00431-014-2467-3. Epub 2014 Dec 13.

DOI:10.1007/s00431-014-2467-3
PMID:25504357
Abstract

UNLABELLED

Functional gastrointestinal disorders (FGIDs) are defined as a variable combination of chronic or recurrent gastrointestinal symptoms not explained by structural or biochemical abnormalities. Infantile colic, gastroesophageal reflux, and constipation are the most common FGIDs that lead to referral to a pediatrician during the first 6 months of life and are often responsible for hospitalization, feeding changes, use of drugs, parental anxiety, and loss of parental working days with relevant social consequences. We performed a retrospective study on patients referred for recurrent abdominal pain from January 2002 trough December 2009 to our Pediatric Gastroenterology Outpatient Unit. The population studied was matched with healthy control without history of recurrent abdominal pain, enrolled among pediatricians practicing primary health care. History of infantile colic, regurgitation, and functional constipation was detected respectively in 26.41, 25.31, and 30.16% of children diagnosed with FGIDs compared to 11.34, 12.85, and 11.76% of healthy children.

CONCLUSION

According to our data, children with a history of gastrointestinal infantile distress have a higher prevalence of FGIDs years later.

摘要

未标注

功能性胃肠疾病(FGIDs)被定义为慢性或复发性胃肠道症状的可变组合,这些症状无法用结构或生化异常来解释。婴儿腹绞痛、胃食管反流和便秘是最常见的功能性胃肠疾病,在出生后的前6个月常导致转诊至儿科医生处,并且常常导致住院、喂养方式改变、用药、家长焦虑以及家长误工天数,产生相关的社会后果。我们对2002年1月至2009年12月转诊至我们儿科胃肠病门诊的复发性腹痛患者进行了一项回顾性研究。所研究的人群与在基层医疗中执业的儿科医生登记的无复发性腹痛病史的健康对照进行匹配。在诊断为功能性胃肠疾病的儿童中,分别有26.41%、25.31%和30.16%有婴儿腹绞痛、反流和功能性便秘病史,而健康儿童中的这一比例分别为11.34%、12.85%和11.76%。

结论

根据我们的数据,有胃肠道婴儿期不适病史的儿童数年后功能性胃肠疾病的患病率更高。

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本文引用的文献

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JAMA Pediatr. 2014 Mar;168(3):228-33. doi: 10.1001/jamapediatrics.2013.4367.
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