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缺血性结肠炎的五个要点:2013年更新

Ischemic colitis in five points: an update 2013.

作者信息

Rania Hefaiedh, Mériam Sabbah, Rym Ennaifer, Hyafa Romdhane, Amine Attaoui, Najet Bel Hadj, Lassad Gharbi, Mohamed Taher Khalfallah

出版信息

Tunis Med. 2014 May;92(5):299-303.

Abstract

BACKGROUND

Ischemic colitis is the most common form of intestinal ischemia. The presence of diarrhea and mild lower gastrointestinal bleeding should guide the diagnosis. Although many laboratory tests and radiographic images may suggest the diagnosis, colonic endoscopic with histological analysis of biopsies is the gold standard for identification of colonic ischemia. aim : The aim of this study was to resume in 5 points: the epidemiology, the clinical features, the diagnostic approach and the management of ischemic colitis in five points. methods: Review of literature. results: Incidence of ischemic colitis was between 3 and 10%. The clinical presentation is predominated by the non gangrenous form associating abdominal pain, tenderness, diarrhea and lower gastrointestinal bleeding. The most frequent causes are represented by systemic hypoperfusion. Laboratory tests can orientate the diagnosis but are unspecific. Radiographic images based on computed tomography or more recently magnetic resonance imaging may suggest the diagnosis, but the confirmation will be given by endoscopic visualization of colonic mucosa with histological analysis of biopsies. Conservative treatment is the most often sufficient to improve colonic lesions. Surgical treatment is reserved for perforations and strictures.

CONCLUSION

The incidence of colonic ischemia is difficult to ascertain. The diagnosis is usually made by medical history, examination, and endoscopy which have become the diagnostic procedure of choice. A high index of suspicion and prompt management are essential for optimum outcomes in patients with colonic ischemia.

摘要

背景

缺血性结肠炎是肠道缺血最常见的形式。腹泻和轻度下消化道出血的存在有助于诊断。尽管许多实验室检查和影像学检查可能提示诊断,但结肠镜检查及活检组织学分析是诊断结肠缺血的金标准。目的:本研究的目的是以五点概括缺血性结肠炎的流行病学、临床特征、诊断方法及治疗。方法:文献回顾。结果:缺血性结肠炎的发病率在3%至10%之间。临床表现以非坏疽型为主,伴有腹痛、压痛、腹泻及下消化道出血。最常见的病因是全身性低灌注。实验室检查可辅助诊断,但缺乏特异性。基于计算机断层扫描或最近的磁共振成像的影像学检查可能提示诊断,但确诊需通过结肠镜观察结肠黏膜并进行活检组织学分析。保守治疗通常足以改善结肠病变。手术治疗适用于穿孔和狭窄。

结论

结肠缺血的发病率难以确定。诊断通常依据病史、检查及内镜检查,内镜检查已成为首选的诊断方法。高度的怀疑指数和及时的治疗对于结肠缺血患者获得最佳预后至关重要。

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