Park Sunyoung, Shin Jung Eun, Han Kiwan, Shin Yu-Bin, Kim Jae-Jin
Department of Psychiatry, Yonsei University College of Medicine , Seoul , South Korea.
Institute of Behavioral Science in Medicine, Yonsei University College of Medicine , Seoul , South Korea.
Front Hum Neurosci. 2014 Nov 24;8:945. doi: 10.3389/fnhum.2014.00945. eCollection 2014.
Social dysfunctions including emotional perception and social decision-making are common in patients with schizophrenia. The aim of this study was to determine the level of intimacy formation and the effect of intimacy on social decision in patients with schizophrenia using virtual reality tasks, which simulate complicated social situations. Twenty-seven patients with schizophrenia and 30 healthy controls performed the 2 virtual social tasks: the intimacy task and the social decision task. The first one was to estimate repeatedly how intimate participants felt with each avatar after listening to what avatars said. The second one was to decide whether or not participants accepted the requests of easy, medium, or hard difficulty by the intimate or distant avatars. During the intimacy task, the intimacy rating scores for intimate avatars were not significantly different between groups, but those for distant avatars were significantly higher in patients than in controls. During the social decision task, the difference in the acceptance rate between intimate and distant avatars was significantly smaller in patients than in controls. In detail, a significant group difference in the acceptance rate was found only for the hard requests, but not for the easy and medium difficulty requests. These results suggest that patients with schizophrenia have a deficit in emotional perception and social decision-making. Various factors such as a peculiarity of emotional deficits, motivational deficits, concreteness, and paranoid tendency may contribute to these abnormalities.
包括情感感知和社交决策在内的社会功能障碍在精神分裂症患者中很常见。本研究的目的是使用虚拟现实任务来确定精神分裂症患者的亲密关系形成水平以及亲密关系对社交决策的影响，该任务模拟复杂的社交情境。27名精神分裂症患者和30名健康对照者完成了两项虚拟社交任务：亲密关系任务和社交决策任务。第一项任务是在听了虚拟角色所说的话后，反复估计参与者对每个虚拟角色的亲密感。第二项任务是决定参与者是否接受亲密或疏远的虚拟角色提出的简单、中等或困难程度的请求。在亲密关系任务中，亲密虚拟角色的亲密评分在两组之间没有显著差异，但疏远虚拟角色的亲密评分在患者中显著高于对照组。在社交决策任务中，患者中亲密和疏远虚拟角色之间的接受率差异显著小于对照组。具体而言，仅在困难请求的接受率上发现了显著的组间差异，而在简单和中等难度请求上没有发现。这些结果表明，精神分裂症患者在情感感知和社交决策方面存在缺陷。各种因素，如情感缺陷的特殊性、动机缺陷、具体性和偏执倾向，可能导致这些异常情况。
