Yoshida Ai, Nakajima Hideaki, Takeura Naoto, Baba Hisatoshi
Nihon Rinsho. 2014 Oct;72(10):1761-7.
The adult population is frequently sustained with ossification of the posterior longitudinal ligament (OPLL) and/or the ligamentum flavum (OLF) of the spine and the diseases may subsequently result is serious spinal cord insult with profound paralysis of the extremities. These pathologies are genetically denoted metaplasia of the elastic fibers of the ligament with consequent ectopic ossification process. The spinal cord is chronically compressed and will result in profound motor paralysis with sensory deficit. Both diseases are well imaged on CT and MRI, showing a various magnitude of spinal cord compression.
成年人群中常出现脊柱后纵韧带骨化（OPLL）和/或黄韧带骨化（OLF），这些疾病随后可能导致严重的脊髓损伤，引起四肢深度瘫痪。这些病理状况在遗传学上被认为是韧带弹性纤维化生，继而发生异位骨化过程。脊髓长期受压会导致严重的运动性瘫痪和感觉障碍。这两种疾病在CT和MRI上都能得到很好的成像，显示出不同程度的脊髓受压。
