Kelly Adrian B, Evans-Whipp Tracy J, Smith Rachel, Chan Gary C K, Toumbourou John W, Patton George C, Hemphill Sheryl A, Hall Wayne D, Catalano Richard F
Centre for Youth Substance Abuse Research, The University of Queensland, Brisbane, Australia.
Addiction. 2015 Apr;110(4):627-35. doi: 10.1111/add.12829. Epub 2015 Jan 26.
Failure to complete high school predicts substantial economic and social disadvantage in adult life. The aim of this study was to determine the longitudinal association of mid-adolescent polydrug use and high school non-completion, relative to other drug use profiles.
A longitudinal analysis of the relationship between polydrug use in three cohorts at grade 9 (age 14-15 years) and school non-completion (reported post-high school).
A State-representative sample of students across Victoria, Australia.
A total of 2287 secondary school students from 152 high schools. The retention rate was 85%.
The primary outcome was non-completion of grade 12 (assessed at age 19-23 years). At grade 9, predictors included 30-day use of eight drugs, school commitment, academic failure and peer drug use. Other controls included socio-economic status, family relationship quality, depressive symptoms, gender, age and cohort.
Three distinct classes of drug use were identified-no drug use (31.7%), mainly alcohol use (61.8%) and polydrug use (6.5%). Polydrug users were characterized by high rates of alcohol, tobacco and cannabis use. In the full model, mainly alcohol users and polydrug users were less likely to complete school than non-drug users [odds ratio (OR) = 1.54, 95% confidence interval (CI) = 1.17-2.03) and OR = 2.51, 95% CI = 1.45-4.33), respectively, P < 0.001]. These effects were independent of school commitment, academic failure, peer drug use and other controls.
Mid-adolescent polydrug use in Australia predicts subsequent school non-completion after accounting for a range of potential confounding factors. Adolescents who mainly consume alcohol are also at elevated risk of school non-completion.
未完成高中学业预示着成年后的巨大经济和社会劣势。本研究的目的是确定青少年中期多药使用和未完成高中学业之间的纵向关联，并与其他药物使用模式进行比较。
对三个队列九年级（14 - 15岁）时的多药使用情况与未完成学业（高中毕业后报告）之间的关系进行纵向分析。
澳大利亚维多利亚州具有州代表性的学生样本。
来自152所高中的2287名中学生。保留率为85%。
主要结局是未完成十二年级学业（在19 - 23岁时评估）。在九年级时，预测因素包括八种药物的30天使用情况、对学校的投入、学业失败和同伴药物使用。其他对照包括社会经济地位、家庭关系质量、抑郁症状、性别、年龄和队列。
确定了三种不同的药物使用类别——不使用药物（31.7%）、主要使用酒精（61.8%）和多药使用（6.5%）。多药使用者的特点是酒精、烟草和大麻使用率高。在完整模型中，主要使用酒精者和多药使用者完成学业的可能性低于不使用药物者[优势比（OR）= 1.54，95%置信区间（CI）= 1.17 - 2.03）和OR = 2.51，95% CI = 1.45 - 4.33），P < 0.001]。这些影响独立于对学校的投入、学业失败、同伴药物使用和其他对照因素。
在考虑一系列潜在混杂因素后，澳大利亚青少年中期的多药使用预示着随后的未完成学业情况。主要饮酒的青少年未完成学业的风险也较高。
