Kapitein S, Wieland J
Tijdschr Psychiatr. 2014;56(12):807-15.
In the Netherlands, many people with an intellectual disability and challenging behavior are still prescribed antipsychotic medication, often for many years and in high doses. According to the new draft law on care and coercion, prescribing antipsychotics, without a valid indication, for people with an intellectual disability, will be regarded as coercion. The effect for clinical practice will be that such antipsychotic medication will have to be re-assessed and, in many cases, reduced and stopped.
To comment on the effectiveness, the side effects and futility of prescribing antipsychotics to people with an intellectual disability and challenging behavior in order to arrive at recommendations about the evaluation of antipsychotics and, if possible, about the reduction of antipsychotics for intellectually challenged people who do not really require such medication.
Practical recommendations are made based on recent literature and clinical experience.
Thorough evaluation and - when possible - the reduction of antipsychotics for people with an intellectual disability requires psychiatrists to invest time and energy in diagnosis and stability of patients, to invest in the patient's environment and to opt for a controlled reduction of antipsychotics.
The new draft law on care and coercion highlights the urgent need for guidelines concerning the reduction of antipsychotics for people with an intellectual disability when there is no clear indication that such a step will benefit the patient.
在荷兰,许多有智力残疾且行为具有挑战性的人仍在长期大剂量服用抗精神病药物。根据新的护理与强制法案草案,在没有有效指征的情况下,为智力残疾者开具抗精神病药物将被视为强制行为。这对临床实践的影响是,此类抗精神病药物必须重新评估,在许多情况下要减少剂量并停药。
对为有智力残疾且行为具有挑战性的人开具抗精神病药物的有效性、副作用及无效性进行评论,以便就抗精神病药物的评估提出建议,若可能,还就为并非真正需要此类药物的智障人士减少抗精神病药物用量提出建议。
基于近期文献和临床经验提出实用建议。
对智力残疾者进行全面评估并尽可能减少其抗精神病药物用量,要求精神科医生投入时间和精力进行诊断及确保患者病情稳定,改善患者的生活环境,并选择逐步减少抗精神病药物用量。
新的护理与强制法案草案凸显了在没有明确迹象表明减少抗精神病药物用量会使患者受益时,为智力残疾者制定相关减药指南的迫切需求。