Simple insoluble cues specify stem cell differentiation.
作者信息
Dingal P C Dave P, Wells Rebecca G, Discher Dennis E
机构信息
Chemical & Biomolecular Engineering and.
Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
出版信息
Proc Natl Acad Sci U S A. 2014 Dec 23;111(51):18104-5. doi: 10.1073/pnas.1421562112. Epub 2014 Dec 15.
Abstract
摘要
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本文引用的文献
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2
Chemically defined generation of human cardiomyocytes.化学定义的人类心肌细胞生成。
Nat Methods. 2014 Aug;11(8):855-60. doi: 10.1038/nmeth.2999. Epub 2014 Jun 15.
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Combining insoluble and soluble factors to steer stem cell fate.结合不溶性和可溶性因子来引导干细胞命运。
Nat Mater. 2014 Jun;13(6):532-7. doi: 10.1038/nmat3997.
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Heart-specific stiffening in early embryos parallels matrix and myosin expression to optimize beating.早期胚胎中心脏特异性硬化与基质和肌球蛋白表达平行，以优化心脏跳动。
Curr Biol. 2013 Dec 2;23(23):2434-9. doi: 10.1016/j.cub.2013.10.057. Epub 2013 Nov 21.
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Reprogramming in vivo produces teratomas and iPS cells with totipotency features.重编程体内产生畸胎瘤和具有全能性特征的 iPS 细胞。
Nature. 2013 Oct 17;502(7471):340-5. doi: 10.1038/nature12586. Epub 2013 Sep 11.
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Nuclear lamin-A scales with tissue stiffness and enhances matrix-directed differentiation.核层粘连蛋白 A 与组织硬度成正比，并增强基质导向的分化。
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Surface-engineered substrates for improved human pluripotent stem cell culture under fully defined conditions.表面工程化的基质在完全定义的条件下提高人类多能干细胞培养。
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