Demir Deniz, Süoğlu Yusufhan, Güven Mehmet, Yılmaz Mahmut Sinan
Department of Otolaryngology, Sakarya University Training and Research Hospital, 54100 Sakarya, Turkey.
Kulak Burun Bogaz Ihtis Derg. 2014 Sep-Oct;24(5):259-64. doi: 10.5606/kbbihtisas.2014.24382.
This study aims to evaluate the prevalence of allergic fungal rhinosinusitis in chronic rhinosinusitis patients in the northwest of Turkey.
Eighty-seven patients diagnosed with chronic rhinosinusitis and who were planned endonasal sinus surgery were enrolled in this prospective study. Patients were evaluated by detailed clinical examination, computed tomography, skin test against allergens, total serum immunoglobulin E (IgE) antibody, fungal-specific IgE antibody, and histopathologic and mycologic monitoring.
Fungal elements showing tissue invasiveness were detected in only four patients. These patients had specific IgE against Aspergillus fumigatus (4.6%). Skin tests were positive for at least one allergen in 16 patients (18.3%).
None of the patients met diagnostic criteria for allergic fungal rhinosinusitis. This result may be due to the diversity in disease prevalence based on geographical location or diagnostic methods.
本研究旨在评估土耳其西北部慢性鼻窦炎患者中变应性真菌性鼻窦炎的患病率。
87例被诊断为慢性鼻窦炎且计划行鼻内鼻窦手术的患者纳入了这项前瞻性研究。通过详细的临床检查、计算机断层扫描、过敏原皮肤试验、血清总免疫球蛋白E（IgE）抗体、真菌特异性IgE抗体以及组织病理学和真菌学监测对患者进行评估。
仅在4例患者中检测到显示组织侵袭性的真菌成分。这些患者有针对烟曲霉的特异性IgE（4.6%）。16例患者（18.3%）的皮肤试验对至少一种过敏原呈阳性。
没有患者符合变应性真菌性鼻窦炎的诊断标准。这一结果可能是由于基于地理位置或诊断方法的疾病患病率差异所致。
