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变应性真菌性鼻-鼻窦炎表现为单侧鼻腔肿物:泰国首例病例报告及文献复习

Allergic fungal rhinosinusitis presented as a unilateral nasal mass: A first case report from Thailand and literature review.

作者信息

Lumyongsatien Jate, Cheunsuchon Pornsuk, Boonyaarunnate Thiraphon

机构信息

Department of Otorhinolaryngology - Head and Neck Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, Thailand.

Department of Pathology, Faculty of Medicine Siriraj Hospital, Mahidol University, Thailand.

出版信息

Ann Med Surg (Lond). 2022 Nov 7;84:104855. doi: 10.1016/j.amsu.2022.104855. eCollection 2022 Dec.

Abstract

BACKGROUND

Allergic fungal rhinosinusitis (AFRS) is a relatively new inflammatory sinonasal disease. Prevalence of the disease is reported to be highly different across Asia.

CASE PRESENTATION

A 23-year-old Thai male came to our hospital with left-sided nasal obstruction. Endoscopic examination found a mass originated from the left sphenoethmoidal recess. Incisional biopsy result of the mass indicated an inflammatory process and high level of serum specific IgE to several aeroallergens was found. Based on the biopsy results and other investigations, the diagnosis of AFRS was made and the patient was treated successfully with endoscopic sinus surgery and postoperative systemic/topical steroids.

DISCUSSION

While AFRS is quite common in some regions, the disease is rarely encountered in Thailand and can be presented as a unilateral lesion, mimicking a tumor mass, which could lead to an incorrect diagnosis and inappropriate treatment.

CONCLUSION

Even though AFRS is rarely reported in our country, it still can be found and might be recognized falsely as a neoplastic process. High level of awareness of the disease features could help to minimize inappropriate disease management.

摘要

背景

变应性真菌性鼻-鼻窦炎(AFRS)是一种相对较新的鼻窦炎性疾病。据报道,该病在亚洲各地的患病率差异很大。

病例报告

一名23岁的泰国男性因左侧鼻塞前来我院就诊。内镜检查发现一个起源于左蝶筛隐窝的肿物。肿物的切开活检结果显示为炎症过程,并且发现血清中对几种气传变应原的特异性IgE水平较高。根据活检结果和其他检查,诊断为AFRS,患者接受了鼻内镜鼻窦手术及术后全身/局部应用类固醇激素治疗,效果良好。

讨论

虽然AFRS在某些地区相当常见,但在泰国很少见,并且可能表现为单侧病变,类似肿瘤肿物,这可能导致错误的诊断和不恰当的治疗。

结论

尽管我国对AFRS的报道很少,但仍可能发现该病,并且可能被误诊为肿瘤性病变。对该病特征的高度认识有助于尽量减少不恰当的疾病管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/edda/9793241/e7285e5111b3/gr1.jpg

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