Minelli Alessandro, Baedke Jan
Department of Biology, University of Padova, Via U. Bassi 58/B, 35131, Padova, Italy,
Hist Philos Life Sci. 2014 Aug;36(1):42-59. doi: 10.1007/s40656-014-0004-3. Epub 2014 Jul 11.
Evolutionary developmental biology (evo-devo) is a rapidly growing discipline whose ambition is to address questions that are of relevance to both evolutionary biology and developmental biology. This field has been increasingly progressing as a new and independent comparative science. However, we argue that evo-devo's comparative approach is challenged by several metaphysical, methodological and socio-disciplinary issues related to the foundation of heuristic functions of model organisms and the possible criteria to be adopted for their selection. In addition, new tools have to be developed to deal with newly chosen model organisms. Therefore, we present a modelling framework suitable to integrate data on individual variation into evo-devo studies on new model organisms and thus to compensate for current idealization practices deliberately suppressing variation.
进化发育生物学（evo-devo）是一门迅速发展的学科，其目标是解决与进化生物学和发育生物学都相关的问题。作为一门新兴的独立比较科学，该领域一直在不断发展。然而，我们认为，evo-devo的比较方法受到了几个形而上学、方法论和社会学科问题的挑战，这些问题涉及模式生物启发功能的基础以及选择模式生物可能采用的标准。此外，必须开发新工具来处理新选择的模式生物。因此，我们提出了一个建模框架，适用于将个体变异数据整合到关于新模型生物的evo-devo研究中，从而弥补当前故意抑制变异的理想化做法。
