Beilin L J
University Department of Medicine Royal Perth Hospital, Western Australia.
Clin Exp Hypertens A. 1989;11(5-6):991-1010. doi: 10.3109/10641968909035387.
Obesity, diet and alcohol consumption constitute major environmental determinations of blood pressure elevation. The long term setting of blood pressure in response to these factors will be determined by genetic susceptibility, and interactions with effects of physical fitness and smoking. Dietary changes which independently influence both atherosclerosis and hypertension are likely to be of greatest value in helping to control morbidity and mortality from hypertensive cardiovascular disease. Recommendations should focus on diets low in total and saturated fat intake and high in fruit and vegetables, containing potassium and fibre, coupled with weight control, alcohol moderation to less than two drinks per day in drinkers and regular physical exercise. Sodium restriction will help lower blood pressure in older hypertensives in particular. The role of dietary calcium or fish oils in blood pressure regulation is still uncertain. Dietary and related recommendations on smoking and exercise should be 'first line' treatment in mild hypertensives, and complimentary to therapy in all patients requiring drugs.
肥胖、饮食和酒精摄入是血压升高的主要环境决定因素。血压对这些因素的长期调节将由遗传易感性以及与身体素质和吸烟影响的相互作用来决定。独立影响动脉粥样硬化和高血压的饮食变化,在帮助控制高血压心血管疾病的发病率和死亡率方面可能具有最大价值。建议应侧重于总脂肪和饱和脂肪摄入量低、水果和蔬菜含量高、富含钾和纤维的饮食,同时控制体重,饮酒适度,饮酒者每天饮酒量少于两杯,并定期进行体育锻炼。限制钠摄入尤其有助于降低老年高血压患者的血压。饮食中的钙或鱼油在血压调节中的作用仍不确定。关于吸烟和运动的饮食及相关建议应作为轻度高血压患者的“一线”治疗方法,并作为所有需要药物治疗患者治疗的补充。