Cipriani Gabriele, Lucetti Claudio, Danti Sabrina, Nuti Angelo
Division of Neurology, Versilia Hospital, Lido di Camaiore, Italy.
Psychogeriatrics. 2015 Mar;15(1):65-74. doi: 10.1111/psyg.12069. Epub 2014 Dec 16.
Sleep is a complex behavioural state, the ultimate functions of which remain poorly understood. It becomes more fragmented as we age, with more night-time awakenings and greater tendency for daytime sleep. The magnitude of disordered sleep among individuals affected by dementia has been clearly demonstrated, and disturbed sleep is a major clinical problem in dementia. Comorbid insomnia and other sleep disturbances are common in patients with neurodegenerative disorders, such Alzheimer's disease and other dementing disorders. How and when sleep problems manifest themselves can depend on the type of dementia involved as well as the stage of the dementia. However, differences in sleep pattern presentation show more variation during the initial stages of dementias than they do during the later stages. Effective, pragmatic interventions are largely anecdotal and untested.
睡眠是一种复杂的行为状态，其最终功能仍知之甚少。随着年龄的增长，睡眠会变得更加碎片化，夜间觉醒次数增多，白天嗜睡倾向增强。痴呆症患者睡眠紊乱的程度已得到明确证实，睡眠障碍是痴呆症的一个主要临床问题。共病性失眠和其他睡眠障碍在神经退行性疾病患者中很常见，如阿尔茨海默病和其他痴呆症。睡眠问题如何以及何时出现，取决于所涉及的痴呆症类型以及痴呆症的阶段。然而，睡眠模式表现的差异在痴呆症初期比后期表现出更多的变化。有效的、实用的干预措施大多是传闻且未经检验的。
