痴呆症患者睡眠障碍的当前治疗方法。
Current treatments for sleep disturbances in individuals with dementia.
作者信息
Deschenes Cynthia L, McCurry Susan M
出版信息
Curr Psychiatry Rep. 2009 Feb;11(1):20-6. doi: 10.1007/s11920-009-0004-2.
Abstract
Sleep disturbances are widespread among older adults. Degenerative neurologic disorders that cause dementia, such as Alzheimer's disease and Parkinson's disease, exacerbate age-related changes in sleep, as do many common comorbid medical and psychiatric conditions. Medications used to treat chronic illness and insomnia have many side effects that can further disrupt sleep and place patients at risk for injury. This article reviews the neurophysiology of sleep in normal aging and sleep changes associated with common dementia subtypes and comorbid conditions. Current pharmacologic and nonpharmacologic evidence-based treatment options are discussed, including the use of light therapy, increased physical and social activity, and multicomponent cognitive-behavioral interventions for improving sleep in institutionalized and community-dwelling adults with dementia.
摘要
睡眠障碍在老年人中普遍存在。导致痴呆的退行性神经疾病，如阿尔茨海默病和帕金森病，会加剧与年龄相关的睡眠变化，许多常见的合并内科和精神疾病也会如此。用于治疗慢性病和失眠的药物有许多副作用，可能会进一步扰乱睡眠，并使患者面临受伤风险。本文综述了正常衰老过程中的睡眠神经生理学以及与常见痴呆亚型和合并症相关的睡眠变化。文中讨论了当前基于证据的药物和非药物治疗选择，包括使用光疗法、增加身体活动和社交活动，以及采用多成分认知行为干预措施来改善患有痴呆症的机构养老和社区居住成年人的睡眠。
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