Berrut Gilles, Vainchtock Alexandre, Fernandez José, Bresse Xavier, Baptiste Charles, De Decker Laure
Pôle hospitalo-universitaire gérontologie clinique, Centre hospitalo-universitaire, Nantes, France.
Évaluation de l'économie de la santé, Lyon, France.
Geriatr Psychol Neuropsychiatr Vieil. 2014 Dec;12(4):395-401. doi: 10.1684/pnv.2014.0505.
Herpes zoster secondary to reactivation and replication of the varicella zoster virus (VZV) caused a painful disease which impact the quality of life. Among the complications, herpes zoster ophtalmicus was responsible to post-herpetic neuralgia and lesions of the ocular globus. The aim of this study is to evaluated the burden and cost of herpes zoster in secondary care in France with focus on herpes zoster ophtalmicus (HZO).
This retrospective analysis was performed using data extracted from the French medical information system during the year 2012. The diagnosis are coded using the international classification of diseases as primary, related or significant associated diagnosis.
During the year 2012, 2,509 patients 50 years old and more were admitted secondary to HZ. Among them, 495 were admitted with an HZO (19.7%). The mean age of patients hospitalized were 77 years. The average cost per stay varied between 3,370 euros and 9,191 euros respectively for zoster without complications and for encephalitis. The overall total hospitalization due to HZ and its complications was around 10.2 million euros in France in 2012, 18% of these costs were attributable to hospitalizations for HZO.
This study evaluated the cost of hospitalization due to zoster for the French health insurance. This total costs were probably underestimate because the non-exhaustiveness of CIM coding. This study shows the burden of zoster and his cost particularly heavy when ophtalmicus or neurological complications were associated to HZ.
水痘带状疱疹病毒（VZV）再激活和复制继发的带状疱疹会引发一种疼痛性疾病，影响生活质量。在并发症中，眼部带状疱疹会导致疱疹后神经痛和眼球病变。本研究的目的是评估法国二级医疗中带状疱疹的负担和成本，重点是眼部带状疱疹（HZO）。
本回顾性分析使用了从2012年法国医疗信息系统中提取的数据。诊断按照国际疾病分类编码为主要、相关或显著相关诊断。
2012年，2509名50岁及以上的患者因带状疱疹入住二级医疗机构。其中，495人因眼部带状疱疹入院（19.7%）。住院患者的平均年龄为77岁。无并发症的带状疱疹和脑炎患者每次住院的平均费用分别在3370欧元至9191欧元之间。2012年，法国因带状疱疹及其并发症导致的住院总费用约为1020万欧元，其中18%的费用归因于眼部带状疱疹的住院治疗。
本研究评估了法国医疗保险中带状疱疹的住院费用。由于国际疾病分类编码不全面，这些总费用可能被低估了。本研究表明，当眼部或神经并发症与带状疱疹相关时，带状疱疹的负担及其成本尤其高昂。
