Blein Cecile, Gavazzi Gaetan, Paccalin Marc, Baptiste Charles, Berrut Gilles, Vainchtock Alexandre
HEVA, Lyon, France.
Université de Grenoble-Alpes et GREPI, clinique universitaire de médecine gériatrique, CHU de Grenoble, la tronche, France.
BMC Infect Dis. 2015 Aug 19;15:350. doi: 10.1186/s12879-015-1059-9.
The objectives of this study were to describe hospital stays related to HZ and to evaluate the direct and indirect cost of hospitalizations due to HZ among patients aged over 50 years.
The hospitalizations of people aged over 50 years were selected from the French national hospital 2011 database (PMSI) using ICD-10 diagnosis codes for HZ. Firstly, stays with HZ as principal or related diagnostic were described through the patient characteristics, type of hospitalization and the related costs. Secondly, a retrospective case-control analysis was performed on stays with HZ as comorbidity in 5 main hospitalizations causes (circulatory, respiratory, osteo-articular, digestive systems and diabetes) to assess the impact of HZ as co-morbidity on the length of stay, mortality rate and costs.
In the first analysis, 2,571 hospital stays were collected (60 % of women, mean age: 76.3 years and mean LOS: 9.5 days). The total health assurance costs were 10,8 M€. Mean cost per hospital stay was 4,206€. In the second analysis, a significant difference in LOS and costs was shown when HZ was associated as comorbidity in other hospitalization's causes.
HZ directly impacts on the hospital cost. When present as comorbidity for other medical reasons, HZ significantly increases the length of hospital stay with subsequent economic burden for the French Health System.
本研究的目的是描述与带状疱疹(HZ)相关的住院情况,并评估50岁以上患者因HZ住院的直接和间接费用。
使用ICD - 10中HZ的诊断代码,从法国国家医院2011年数据库(PMSI)中选取50岁以上人群的住院病例。首先,通过患者特征、住院类型和相关费用来描述以HZ作为主要或相关诊断的住院情况。其次,对在5种主要住院原因(循环系统、呼吸系统、骨关节、消化系统和糖尿病)中HZ作为合并症的住院病例进行回顾性病例对照分析,以评估HZ作为合并症对住院时间、死亡率和费用的影响。
在首次分析中,收集到2571例住院病例(60%为女性,平均年龄:76.3岁,平均住院时间:9.5天)。医疗保障总费用为1080万欧元。每次住院的平均费用为4206欧元。在第二次分析中,当HZ作为其他住院原因的合并症时,住院时间和费用显示出显著差异。
HZ直接影响医院费用。当HZ作为其他医疗原因的合并症出现时,会显著增加住院时间,给法国医疗系统带来后续经济负担。