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一名50岁女性经体外受精-胚胎移植并使用自体卵母细胞后成功分娩:一例罕见病例报告。

Live birth in a 50-year-old woman following in vitro fertilization-embryo transfer with autologous oocytes: a rare case report.

作者信息

Rani Geetha, Goswami Sourendra, Chattopadhyay Ratna, Ghosh Sanghamitra, Chakravarty Baidyanath, Ganesh Ashalatha

机构信息

Institute of Reproductive Medicine, Kolkata, India.

Institute of Reproductive Medicine, Kolkata, India.

出版信息

Fertil Steril. 2015 Feb;103(2):414-6. doi: 10.1016/j.fertnstert.2014.11.006. Epub 2014 Dec 13.

Abstract

OBJECTIVE

To report a live birth with in vitro fertilization (IVF) from a 50-year-old woman with homologous oocytes.

DESIGN

Case report.

SETTING

Referral center.

PATIENT(S): A 50-year-old woman.

INTERVENTION(S): IVF with fresh embryo transfer (ET).

MAIN OUTCOME MEASURE(S): Live birth after IVF.

RESULT(S): A 50-year-old woman conceived with her own oocytes by means of IVF. Three fresh embryos were transferred, resulting in a pregnancy and delivery by cesarean section at 35 weeks of a healthy male baby weighing 2,300 g.

CONCLUSION(S): Extensive literature search suggests that this is the first case report of live birth in a 50-year-old woman after IVF-ET with her own oocytes. This is a very rare and unusual case that deviates from the norm and therefore warrants attention. In selected cases, assisted reproductive technology might be reasonable to try for a limited number of times with a woman's own oocytes.

摘要

目的

报告一例50岁女性使用自身卵母细胞通过体外受精(IVF)实现活产的病例。

设计

病例报告。

地点

转诊中心。

患者

一名50岁女性。

干预措施

新鲜胚胎移植(ET)的IVF。

主要观察指标

IVF后的活产情况。

结果

一名50岁女性通过IVF使用自身卵母细胞受孕。移植了3枚新鲜胚胎,妊娠后于35周行剖宫产分娩出一名体重2300g的健康男婴。

结论

广泛的文献检索表明,这是首例50岁女性使用自身卵母细胞经IVF-ET后活产的病例报告。这是一个非常罕见且不寻常的病例,偏离了常规,因此值得关注。在特定病例中,使用女性自身卵母细胞尝试有限次数的辅助生殖技术可能是合理的。

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