Changhua Christian Hospital Reproductive Medicine Center, Taiwan.
Changhua Christian Hospital Reproductive Medicine Center, Taiwan.
Taiwan J Obstet Gynecol. 2022 May;61(3):551-554. doi: 10.1016/j.tjog.2022.03.028.
Advanced maternal age and decreased ovarian reserve have been challenges for assisted reproductive technology (ART). Few cases, using autologous oocytes more than 46-years-old, have previously been reported. We seek to show how the age at which autologous oocytes may successfully be employed may be increasing.
We report a 47-year-old woman with an anti-Müllerian hormone (AMH) level of 0.24 ng/mL, conceived through in vitro fertilization (IVF) using autologous oocytes. Patient was given an antagonist protocol for ovarian stimulation and one frozen-thawed embryo was transferred. The patient became pregnant. The course of her pregnancy was uneventful and she gave birth to a 3330 gm male baby by cesarean section.
Technological advances permit women, who previously would have been considered too old to employ an autologous oocyte, to have a successful pregnancy with a live birth.
高龄和卵巢储备功能下降一直是辅助生殖技术（ART）面临的挑战。此前已有少数使用 46 岁以上自体卵的病例报告。我们旨在展示使用自体卵成功的年龄可能正在增加。
我们报告了一例 47 岁的女性，其抗苗勒管激素（AMH）水平为 0.24ng/mL，通过体外受精（IVF）使用自体卵受孕。患者采用拮抗剂方案进行卵巢刺激，移植了一枚冷冻解冻胚胎。患者怀孕了。她的妊娠过程顺利，通过剖宫产娩出一名 3330 克重的男婴。
技术进步使以前被认为年龄太大而无法使用自体卵的女性能够成功怀孕并分娩活婴。
