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沿布拉斯科线分布的巨大多灶性皮肤血管瘤伴心力衰竭,采用普萘洛尔治疗。

Large multifocal cutaneous hemangioma along lines of Blaschko with cardiac failure treated with propranolol.

作者信息

Khanna Deepshikha, Chakravarty Payal, Arora Pooja, Jain Rahul, Mittal Medha

机构信息

Department of Dermatology, Chacha Nehru Bal Chikitsalaya, Delhi, India.

出版信息

Pediatr Dermatol. 2015 Jan-Feb;32(1):e18-22. doi: 10.1111/pde.12476. Epub 2014 Dec 16.

Abstract

Hemangiomas are classified as focal or segmental according to the morphology and distribution of lesions. Congestive cardiac failure is frequently encountered in diffuse hepatic hemangiomas due to high-volume shunting and rarely in hemangiomas confined to the skin. We report here the case of a large multifocal hemangioma along the lines of Blaschko with high-output cardiac failure, with improvement in cutaneous and hemodynamic symptoms after propranolol therapy. Presentation along the lines of Blaschko raises the possibility of hemangiomas arising as a result of mosaicism.

摘要

根据病变的形态和分布,血管瘤可分为局灶性或节段性。由于大量分流,弥漫性肝血管瘤常伴有充血性心力衰竭,而局限于皮肤的血管瘤则很少见。我们在此报告一例沿Blaschko线分布的大型多灶性血管瘤伴高输出量心力衰竭的病例,普萘洛尔治疗后皮肤和血流动力学症状有所改善。沿Blaschko线出现提示血管瘤可能是由于镶嵌现象引起的。

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