Primary Care Clinical Sciences, School of Health and Population Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
BJOG. 2015 Mar;122(4):565-75. doi: 10.1111/1471-0528.13193. Epub 2014 Dec 17.
To investigate the effectiveness of exercise as treatment for vasomotor menopausal symptoms.
Three-group randomised controlled trial, two exercise interventions and a control group.
Primary Care, West Midlands UK.
Perimenopausal and postmenopausal women experiencing at least five hot flushes/night sweats per day and not taken MHT in previous 3 months were recruited from 23 general practices.
Participants in both exercise interventions groups were offered two face-to-face consultations with a physical activity facilitator to support engagement in regular exercise. In addition, one exercise group received a menopause-specific information DVD and written materials to encourage regular exercise and the other exercise group was offered the opportunity to attend exercise social support groups in their communities. Interventions lasted 6 months.
The primary outcome was frequency of hot flushes/night sweats at 6-month up.
Two hundred and sixty-one women were randomised (n = 87 per group). Neither of the exercise intervention groups reported significantly less frequent hot flushes/night sweats per week than controls (exercise-DVD versus control: -8.9, 95% CI -20.0 to 2.2; exercise-social support versus control: -5.2, 95% CI -16.7 to 6.3).
This trial indicates that exercise is not an effective treatment for hot flushes/night sweats. Contrary to current clinical guidance, women should not be advised that exercise will relieve their vasomotor menopausal symptoms.
研究运动作为治疗血管舒缩性更年期症状的有效性。
三组随机对照试验，两种运动干预和对照组。
英国西米德兰兹郡的初级保健机构。
经历至少每天 5 次热潮/盗汗且在过去 3 个月内未服用 MHT 的围绝经期和绝经后妇女，从 23 家普通诊所招募。
两个运动干预组的参与者都接受了两次与体育活动促进者的面对面咨询，以支持他们定期进行锻炼。此外，一组运动组收到了专门针对更年期的信息 DVD 和书面材料，以鼓励定期锻炼，另一组运动组则有机会参加社区内的运动社交支持小组。干预持续 6 个月。
主要结局是 6 个月时热潮/盗汗的频率。
261 名女性被随机分组（每组 87 名）。两个运动干预组报告的每周热潮/盗汗频率均不比对照组少（运动-DVD 组与对照组相比：-8.9，95%CI -20.0 至 2.2；运动社交支持组与对照组相比：-5.2，95%CI -16.7 至 6.3）。
这项试验表明，运动并不是治疗热潮/盗汗的有效方法。与当前的临床指南相反，不应建议女性运动可以缓解她们的血管舒缩性更年期症状。
