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以脊髓病为表现的小脑幕硬脑膜动静脉瘘:病例系列及文献综述

Tentorial dural arteriovenous fistula presenting as myelopathy: Case series and review of literature.

作者信息

Gross Robert, Ali Rushna, Kole Max, Dorbeistein Curtis, Jayaraman Mahesh V, Khan Muhib

机构信息

Robert Gross, Muhib Khan, Department of Neurology, Warren Alpert Medical School of Brown University, Providence, RI 02903, United States.

出版信息

World J Clin Cases. 2014 Dec 16;2(12):907-11. doi: 10.12998/wjcc.v2.i12.907.

Abstract

Dural arteriovenous fistula (DAVF) is a rare type of cerebral arteriovenous malformation. Common presenting symptoms are related to hemorrhage. However, rarely these patients may present with myelopathy. We present two cases of DAVF presenting as rapidly progressive myelopathy. Two treatment options are available: microsurgical interruption of the fistula and endovascular embolization. These treatment options of DAVFs have improved significantly in the last decade. The optimal treatment of DAVFs remains controversial, and there is an ongoing debate as to whether primary endovascular or primary microsurgical treatment is the optimal management for these lesions. However, despite treatment a high percentage of patients are still left with severe disability. The potential for functional ambulation in patients with DAVF is related to the time of intervention. This emphasizes the important of early diagnosis and early intervention in DAVF. The eventual outcome may depend on several factors, such as the duration of symptoms, the degree of disability before treatment, and the success of the initial procedure to close the fistula. The usage of magnetic resonance imaging and selective angiography has significantly improved the ability to characterize DAVFs, however, these lesions remain inefficiently diagnosed. If intervention is delayed even prolonged time in rehabilitation does not change the grave prognosis. This review outlines the presentation, classication and management of DAVF as well as discussing patient outcomes.

摘要

硬脑膜动静脉瘘(DAVF)是一种罕见的脑动静脉畸形。常见的临床表现与出血有关。然而,这些患者很少会出现脊髓病。我们报告两例表现为快速进展性脊髓病的DAVF。有两种治疗选择:瘘口的显微手术阻断和血管内栓塞。在过去十年中,DAVF的这些治疗选择有了显著改善。DAVF的最佳治疗仍存在争议,关于原发性血管内治疗还是原发性显微手术治疗是这些病变的最佳管理方式,目前仍在争论。然而,尽管进行了治疗,仍有很大比例的患者留有严重残疾。DAVF患者功能行走的可能性与干预时间有关。这强调了DAVF早期诊断和早期干预的重要性。最终结果可能取决于几个因素,如症状持续时间、治疗前的残疾程度以及关闭瘘口的初始手术的成功率。磁共振成像和选择性血管造影的应用显著提高了对DAVF的特征化能力,然而,这些病变的诊断效率仍然低下。如果干预延迟,即使长时间的康复也不会改变严重的预后。本综述概述了DAVF的表现、分类和管理,并讨论了患者的预后。

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Spinal dural arteriovenous fistulae: clinical features and long-term results.脊髓硬脊膜动静脉瘘:临床特征与长期结果
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Tentorial dural arteriovenous fistulas.小脑幕硬脑膜动静脉瘘
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