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大麻素呕吐综合征长期随访病例

Case of cannabinoid hyperemesis syndrome with long-term follow-up.

作者信息

Cha Jae Myung, Kozarek Richard A, Lin Otto S

机构信息

Jae Myung Cha, Gastroenterology Division, Department of Internal Medicine, Kyung Hee University Hospital at Gang Dong, Kyung Hee University School of Medicine, Seoul 134-727, South Korea.

出版信息

World J Clin Cases. 2014 Dec 16;2(12):930-3. doi: 10.12998/wjcc.v2.i12.930.

DOI:10.12998/wjcc.v2.i12.930
PMID:25516874
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4266847/
Abstract

Long-term cannabis use may be associated with attacks of severe nausea and vomiting, and a characteristic learned behavior of compulsive hot bathing, termed cannabinoid hyperemesis syndrome (CHS). Long-term follow-up and prognosis of CHS have not been reported previously. A 44-year-old Caucasian man with a long history of addiction to marijuana presented with chronic abdominal pain complicated by attacks of uncontrollable vomiting for 16 years. He had a compulsion to take scalding hot showers, as many as 15 times a day, to relieve his symptoms. All previous therapies had been ineffective. However, abstinence from marijuana led to rapid and complete resolution of all symptoms and his compulsive hot showering behavior. He has been followed for nine years, and is still doing well without recurrence of symptoms. Physicians should have a high index of suspicion for this under-recognized condition, as excellent long-term prognosis of CHS can be achieved when abstinence is maintained.

摘要

长期使用大麻可能与严重恶心和呕吐发作以及一种被称为大麻素 hyperemesis 综合征(CHS)的强迫性热水浴习得行为有关。此前尚未报道过 CHS 的长期随访和预后情况。一名有长期大麻成瘾史的 44 岁白人男性,出现慢性腹痛并伴有无法控制的呕吐发作 16 年。他有强迫性洗滚烫热水澡的行为,每天多达 15 次,以缓解症状。此前所有治疗均无效。然而,戒除大麻后所有症状迅速且完全缓解,其强迫性热水浴行为也消失了。他已被随访九年,目前情况良好,症状未复发。医生应对这种未被充分认识的病症保持高度怀疑,因为保持戒除状态时 CHS 可实现良好的长期预后。

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