快照：慢性淋巴细胞白血病。

SnapShot: chronic lymphocytic leukemia.

机构信息

Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

出版信息

Cancer Cell. 2014 Nov 10;26(5):770-770.e1. doi: 10.1016/j.ccell.2014.10.020.

DOI:10.1016/j.ccell.2014.10.020

PMID:25517752

Abstract

Chronic lymphocytic leukemia (CLL) is the most common leukemia among adults in western countries. This SnapShot depicts the origins and evolution of this B cell malignancy, describes prognostic factors and CLL animal models, and illustrates therapies in preclinical and clinical development against CLL.

摘要

慢性淋巴细胞白血病（CLL）是西方国家成年人中最常见的白血病。这篇 SnapShot 描绘了这种 B 细胞恶性肿瘤的起源和演变，描述了预后因素和 CLL 动物模型，并说明了针对 CLL 的临床前和临床开发中的治疗方法。