Ten Hacken Elisa, Guièze Romain, Wu Catherine J
Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, USA.
CHU Clermont-Ferrand, Hématologie Clinique, Clermont-Ferrand, France.
Cancer Cell. 2017 Nov 13;32(5):716-716.e1. doi: 10.1016/j.ccell.2017.10.015.
Despite the recent advances in the therapeutic management of Chronic Lymphocytic Leukemia (CLL) patients, this common B cell malignancy still remains incurable. This SnapShot provides an overview of CLL biology and therapy, with a focus on genetics and microenvironmental interactions, which contribute to disease progression and therapy resistance. To view this SnapShot, open or download the PDF.
尽管在慢性淋巴细胞白血病（CLL）患者的治疗管理方面最近取得了进展，但这种常见的B细胞恶性肿瘤仍然无法治愈。本简要概述提供了CLL生物学和治疗的概述，重点关注遗传学和微环境相互作用，这些因素导致疾病进展和治疗耐药性。要查看此简要概述，请打开或下载PDF。
