Di Bonaventura Giovanni, Pompilio Arianna, Crocetta Valentina, De Nicola Serena, Barbaro Filippo, Giuliani Livio, D'Emilia Enrico, Fiscarelli Ersilia, Bellomo Rosa Grazia, Saggini Raoul
Department of Experimental & Clinical Sciences, G. d'Annunzio University of Chieti-Pescara, Chieti, Italy.
Future Microbiol. 2014;9(12):1303-17. doi: 10.2217/fmb.14.96.
To evaluate the in vitro effects of extremely low-frequency magnetic field (ELF-MF) on growth and biofilm formation by Staphylococcus aureus, Pseudomonas aeruginosa, Burkholderia cepacia and Stenotrophomonas maltophilia strains from cystic fibrosis patients.
MATERIALS & METHODS: The motion of selected ions (Fe, Ca, Cu, Zn, Mg, K, Na) was stimulated by the ion resonance effect, then influence on growth and biofilm formation/viability was assessed by spectrophotometry or viability count.
Generally, exposure to ELF-MF significantly increased bacterial growth and affected both biofilm formation and viability, although with differences with regard to ions and species considered.
Exposure to ELF-MF represents a possible new approach for treatment of biofilm-associated cystic fibrosis lung infections.
评估极低频磁场（ELF-MF）对来自囊性纤维化患者的金黄色葡萄球菌、铜绿假单胞菌、洋葱伯克霍尔德菌和嗜麦芽窄食单胞菌菌株生长及生物膜形成的体外影响。
通过离子共振效应刺激选定离子（铁、钙、铜、锌、镁、钾、钠）的运动，然后通过分光光度法或活菌计数评估其对生长及生物膜形成/活力的影响。
总体而言，暴露于极低频磁场显著增加细菌生长，并影响生物膜形成和活力，尽管在所考虑的离子和菌种方面存在差异。
暴露于极低频磁场是治疗与生物膜相关的囊性纤维化肺部感染的一种可能的新方法。
