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心脏病中的心脏能量代谢受损及代谢调节剂的潜在作用:临床医生综述

Cardiac energetic impairment in heart disease and the potential role of metabolic modulators: a review for clinicians.

作者信息

Singh Satnam, Schwarz Konstantin, Horowitz John, Frenneaux Michael

机构信息

From the Department of Cardiovascular Medicine, University of Aberdeen, Aberdeen, United Kingdom (S.S., K.S., M.F.); and Cardiology Unit, The Queen Elizabeth Hospital, Adelaide, Australia (J.H.).

出版信息

Circ Cardiovasc Genet. 2014 Oct;7(5):720-8. doi: 10.1161/CIRCGENETICS.114.000221.

Abstract

Cardiac energetic impairment is a frequent finding in patients with both inherited and acquired diseases of heart muscle. In this review the mechanisms of energy generation in the healthy heart and their disturbances in heart muscle diseases are described. Therapeutic agents targeted at correcting cardiac energetic impairment are discussed.

摘要

心肌能量代谢受损在遗传性和获得性心肌疾病患者中很常见。本文综述了健康心脏中能量产生的机制及其在心肌疾病中的紊乱情况。并讨论了针对纠正心肌能量代谢受损的治疗药物。

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