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Natural cycle, modified natural cycle and mild stimulation are different protocols which provide some advantages compared to conventional stimulation: lower medication cost, less injections, less invasive, low risk of ovarian hyperstimulation and multiple pregnancy. There main drawback is high cancellation rate due to premature ovulation and lack of egg recovery at the retrieval. When an embryo transfer can be performed, the cumulative pregnancy rate is similar to the results in con- ventional stimulation. Those protocols don't provide any advantage in term of results for woman with normal ovarian reserve, however it might be considered as a therapeutic alternative in poor responders.
自然周期、改良自然周期和温和刺激是不同的方案,与传统刺激相比具有一些优势:药物成本较低、注射次数较少、侵入性较小、卵巢过度刺激和多胎妊娠风险较低。其主要缺点是由于过早排卵和取卵时未获得卵子而导致取消率较高。当可以进行胚胎移植时,累积妊娠率与传统刺激的结果相似。对于卵巢储备正常的女性,这些方案在结果方面没有任何优势,然而,对于反应不良者,它可能被视为一种治疗选择。