Kessler Brice A, Bookhout Christine, Jaikumar Sivakumar, Hipps John, Lee Yueh Z
University of North Carolina School of Medicine, University of North Carolina, Chapel Hill, North Carolina.
Department of Pathology, University of North Carolina, Chapel Hill, North Carolina.
Clin Imaging. 2015 Mar-Apr;39(2):300-4. doi: 10.1016/j.clinimag.2014.11.018. Epub 2014 Nov 26.
We report the neuroimaging and histopathologic findings of a 12-year-old female patient with a disseminated oligodendroglial-like leptomeningeal tumor with anaplastic progression and presumed extraneural metastatic disease. These tumors may represent distinct pathology primarily seen in pediatric patients. Neuroimaging demonstrates diffuse, progressive enhancement of the leptomeninges often with interval development of intraparenchymal lesions on follow-up. Disease is typically confined to the central nervous system, though diffuse peritoneal disease was seen in our case, possibly through metastatic seeding of the abdomen via ventriculoperitoneal shunt.
我们报告了一名12岁女性患者的神经影像学和组织病理学检查结果，该患者患有弥漫性少突胶质细胞样软脑膜肿瘤，伴有间变性进展及推测的神经外转移疾病。这些肿瘤可能代表主要见于儿科患者的独特病理学表现。神经影像学显示软脑膜弥漫性、进行性强化，随访时常常出现脑实质内病变。尽管在我们的病例中可见弥漫性腹膜疾病，可能是通过脑室腹腔分流导致腹部转移播散，但疾病通常局限于中枢神经系统。
