Teoh Suliana, Hofer Monika, Kerr Richard, Warner Nicola, Kueker Wilhelm, Rothwell Peter M, Zamboni Giovanna
1 Department of Oncology, Oxford University Hospitals NHS Foundation Trust.
2 Nuffield Department of Clinical Neuroscience, University of Oxford, UK.
Neuroradiol J. 2019 Feb;32(1):53-56. doi: 10.1177/1971400918793530. Epub 2018 Aug 9.
This article describes an unusual presentation of disseminated oligodendroglial-like leptomeningeal tumour. A previously healthy 23-year-old Caucasian woman presented with headache, photophobia and recurrent seizures. Initial investigations were suggestive of subarachnoid haemorrhage. Her symptoms deteriorated rapidly and within weeks she developed complete blindness and diffuse sensory ataxia. The aim of this article is to increase awareness of this rare disease, especially in patients who present with acute, rapidly progressive neurological symptoms with signs of acute or chronic central nervous system bleeding.
本文描述了一种罕见的播散性少突胶质细胞样软脑膜肿瘤表现。一名既往健康的23岁白种女性出现头痛、畏光和反复发作的癫痫。初步检查提示蛛网膜下腔出血。她的症状迅速恶化,数周内就发展为完全失明和弥漫性感觉性共济失调。本文旨在提高对这种罕见疾病的认识,尤其是对于那些出现急性、快速进展的神经系统症状且伴有急慢性中枢神经系统出血迹象的患者。