Inghilleri M, Berardelli A, Cruccu G, Priori A, Manfredi M
Dipartimento di Scienze Neurologiche, Università di Roma, Italia.
J Neurol Neurosurg Psychiatry. 1989 Aug;52(8):970-4. doi: 10.1136/jnnp.52.8.970.
The descending volley evoked in humans by transcranial electrical stimulation of the scalp was recorded with epidural and spinal electrodes. It consisted of an early wave, which increased in amplitude and decreased in latency when the strength of the stimulus was increased. The mean conduction velocity of the early wave was 66, SD 2.5 m/s. At high stimulus intensity this wave was followed by later and smaller waves, which travel at the same speed as the initial potential. The recovery cycle of the descending volley was studied by delivering paired cortical stimuli at time intervals ranging from 0.5 to 10 ms. The early wave evoked by the test stimulus recovered to about 50% at a 1 ms interval and to 100% at a 3.5 ms interval. The later waves could not be tested at short time intervals but with time intervals longer than 3.5 ms they recovered to 100%. It is suggested that the initial and later waves after scalp stimulation are equivalent to the D and I waves seen in animal experiments.
通过经颅电刺激头皮在人体诱发的下行性波群，用硬膜外和脊髓电极进行记录。它由一个早波组成，当刺激强度增加时，其波幅增大而潜伏期缩短。早波的平均传导速度为66，标准差为2.5米/秒。在高刺激强度下，该波之后是较晚出现且较小的波，它们的传播速度与初始电位相同。通过以0.5至10毫秒的时间间隔给予成对的皮层刺激来研究下行性波群的恢复周期。测试刺激诱发的早波在1毫秒间隔时恢复到约50%，在3.5毫秒间隔时恢复到100%。较晚的波在短时间间隔内无法测试，但在时间间隔长于3.5毫秒时它们恢复到100%。有人提出，头皮刺激后的初始波和较晚的波相当于动物实验中看到的D波和I波。
