Clinical analysis of twenty cases of cervical cancer associated with pregnancy.

OBJECTIVES

The objectives are to investigate the therapeutic methods and prognosis of cervical cancer associated with pregnancy.

METHODS

Combined with a literature review, we analyzed the clinical characteristics, diagnosis and treating process, and prognosis of 20 cases of cervical cancer associated with pregnancy admitted in our hospital from 2000 to 2009.

RESULTS

Fifteen cases were treated with surgery, four cases with radiotherapy or synchronous chemoradiation, and one case with palliative systemic chemotherapy. Fourteen cases were disease-free survivals, five cases died of distant metastasis, and one case was lost to follow-up. Also, for survival, there were seven in eight cases of early pregnancy, two in four cases of mid-pregnancy, one in two cases of late pregnancy, four in six postpartum cases, and one in three cases of vaginal delivery.

CONCLUSIONS

There was a close relationship between clinical stage, diagnosis time, delivery method, and the prognosis of cervical cancer associated with pregnancy. For late pregnancy and postpartum cervical cancer surgery, preoperative and postoperative combination chemotherapy might improve the prognosis.